| Sumter Electric Cooperative INC | Utilities | $8,441,200 | $8,537,638 | 399 | N/A | Research |
| Project Health INC | Health Care and Social Assistance | $2,014,270 | $2,037,266 | 203 | N/A | Research |
| Project Health | Health Care and Social Assistance | $2,000,000 | $2,018,611 | 252 | N/A | Research |
| Specialized Services Logistics | Transportation and Warehousing | $1,777,800 | $1,794,983 | 119 | $24.0M | Research |
| Specialized Services Logistics | Transportation and Warehousing | $1,777,749 | $1,795,429 | 80 | $16.1M | Research |
| Florida Designer Cabinets, INC | Manufacturing | $165,735 | $167,797 | 17 | <$5M | Research |
| Weaver Aggregate Transport Inc. | Transportation and Warehousing | $150,017 | $150,988 | 14 | <$5M | Research |
| Daniel D. Richardson, O.d., P.a. | Health Care and Social Assistance | $50,700 | $51,068 | 5 | <$5M | Research |
| All Terrain Veg. Management Inc. | Construction | $40,000 | $40,296 | 3 | <$5M | Research |
| Blackjack Sporting Clays LLC | Unknown | $36,800 | $37,324 | 7 | N/A | Research |
| Sumter Pediatrics PA | Health Care and Social Assistance | $32,810 | $33,017 | 3 | <$5M | Research |
| Sumter Pediatrics PA | Health Care and Social Assistance | $32,500 | $32,776 | 3 | <$5M | Research |
| Better Life Academy Sumter | Educational Services | $27,599 | $27,783 | 5 | <$5M | Research |
| Level One Management LLC | Professional, Scientific, and Technical Services | $20,800 | $20,897 | 1 | <$5M | Research |
| Level One Management LLC | Accommodation and Food Services | $20,800 | $20,998 | 1 | <$5M | Research |
| Varahikrupa 1951 INC | Retail Trade | $17,500 | $17,559 | 1 | <$5M | Research |
| Scott Mann Custom Homes, Inc. | Construction | $16,744 | $16,962 | 2 | <$5M | Research |
| Warren Septic Company, LLC | Construction | $16,100 | $16,213 | 3 | <$5M | Research |
| Scott Hesler | Transportation and Warehousing | $14,125 | $14,211 | 1 | <$5M | Research |
| American Glove & Safety Supply INC | Wholesale Trade | $10,000 | $10,104 | 2 | <$5M | Research |
| Integrity Septic Services INC | Administrative and Support and Waste Management | $7,800 | $7,911 | 1 | <$5M | Research |
| J&b Sales and Service Inc. | Accommodation and Food Services | $7,473 | $7,511 | 4 | <$5M | Research |
| Jimmie L. Douglas Jr. | Agriculture, Forestry, Fishing and Hunting | $6,527 | $6,580 | 1 | <$5M | Research |
| J&b Sales and Service, Inc. | Accommodation and Food Services | $5,338 | $5,407 | 4 | <$5M | Research |
| Robin Cassidy | Other Services (except Public Administration) | $3,656 | $3,682 | 1 | <$5M | Research |