| Gadsden Pediatric Clinic PA | Health Care and Social Assistance | $376,757 | $379,585 | 28 | $8.8M | AI Deep Dive |
| Ctc | Administrative and Support and Waste Management | $375,500 | $378,640 | 50 | $10.8M | AI Deep Dive |
| Clinical Urology Associates PC | Health Care and Social Assistance | $355,700 | $359,832 | 37 | $11.6M | AI Deep Dive |
| Advantage Emergency Medical Services, LLC | Health Care and Social Assistance | $349,500 | $353,102 | 57 | $13.2M | AI Deep Dive |
| Appalachian Newspapers INC | Information | $349,035 | $353,000 | 48 | $8.1M | AI Deep Dive |
| Neo Pt INC | Health Care and Social Assistance | $348,561 | $350,710 | 52 | $14.0M | AI Deep Dive |
| Jerry Pruett | Accommodation and Food Services | $347,242 | $350,714 | 52 | $9.2M | AI Deep Dive |
| A & S Electrical Contractors Inc. | Construction | $336,983 | $339,134 | 29 | $9.5M | AI Deep Dive |
| Neo Pt, Inc. | Health Care and Social Assistance | $323,600 | $327,402 | 46 | $12.4M | AI Deep Dive |
| Sterling Co. | Professional, Scientific, and Technical Services | $306,900 | $308,614 | 38 | N/A | AI Deep Dive |
| Gadsden Country Club | Arts, Entertainment, and Recreation | $306,900 | $308,639 | 66 | $9.2M | AI Deep Dive |
| Crosson Agency, LLC | Professional, Scientific, and Technical Services | $303,500 | $305,447 | 31 | <$5M | AI Deep Dive |
| Gadsden Eye Associates, P.c. | Health Care and Social Assistance | $299,594 | $301,523 | 29 | $9.1M | AI Deep Dive |
| Emad Suleiman DBA Little Ceasar's | Accommodation and Food Services | $297,915 | $300,638 | 100 | $17.8M | AI Deep Dive |
| The Orthopedic Center, LLC | Health Care and Social Assistance | $291,000 | $292,964 | 34 | $10.7M | AI Deep Dive |
| Gadsden Music Company INC | Retail Trade | $288,100 | $289,725 | 37 | $8.7M | AI Deep Dive |
| Rehab Partners PC | Health Care and Social Assistance | $285,869 | $287,686 | 24 | <$5M | AI Deep Dive |
| Rehab Partners P.c. | Health Care and Social Assistance | $285,869 | $287,968 | 22 | $5.9M | AI Deep Dive |
| Jeff Phillips Electrical Construction INC | Construction | $284,144 | $285,738 | 26 | $8.6M | AI Deep Dive |
| Modern Heating and Cooling.inc | Construction | $279,250 | $281,339 | 28 | $8.9M | AI Deep Dive |
| Jeff Phillips Electrical Construction INC | Construction | $275,571 | $276,870 | 30 | $9.9M | AI Deep Dive |
| Pruett's Bar-B-Q, LLC | Accommodation and Food Services | $266,247 | $269,303 | 93 | $16.5M | AI Deep Dive |
| Rep Management, LLC | Retail Trade | $247,500 | $249,480 | 37 | $5.8M | AI Deep Dive |
| Dws Machine Inc. | Manufacturing | $239,000 | $240,241 | 32 | $7.8M | AI Deep Dive |
| D.w.s. Machine, Inc. | Manufacturing | $239,000 | $241,105 | 34 | $8.3M | AI Deep Dive |