| Arizona Community Physicians, P.c. | Health Care and Social Assistance | $10,000,000 | $10,131,667 | 500 | $156.9M |  Research |
| Arizona's Children Association | Other Services (except Public Administration) | $7,459,585 | $7,502,063 | 500 | $95.5M | Research |
| Kalil Bottling Co. | Manufacturing | $7,138,627 | $7,231,516 | 500 | $176.5M | Research |
| Cs Rental Properties, LLC | Professional, Scientific, and Technical Services | $6,604,532 | $6,679,200 | 324 | $40.0M | Research |
| Morrison, Ekre & Bart Management Services, Inc. | Real Estate and Rental and Leasing | $6,565,063 | $6,638,674 | 500 | $75.0M | Research |
| Serrato Corporation | Educational Services | $6,194,435 | $5,876,641 | 500 | $105.0M | Research |
| Pueblo Mechanical and Controls, LLC | Construction | $6,126,592 | $6,195,346 | 480 | $151.9M | Research |
| Pima Heart Physicians, P.c. | Health Care and Social Assistance | $4,823,080 | $4,879,799 | 411 | $129.0M | Research |
| Accelerate Diagnostics, Inc. | Health Care and Social Assistance | $4,780,600 | $4,840,194 | 237 | $54.9M | Research |
| Codac Health, Recovery & Wellness, Inc. | Health Care and Social Assistance | $4,737,775 | $4,792,588 | 297 | N/A | Research |
| International Cooling Tower USA INC | Construction | $4,710,522 | $4,761,160 | 330 | $108.6M | Research |
| Sam Levitz Furniture Company, INC | Retail Trade | $4,673,150 | $4,732,301 | 500 | $90.6M | Research |
| Royal Speedway INC | Retail Trade | $4,304,878 | $4,096,043 | 373 | $94.0M | Research |
| Academy of Mathematics and Science South INC | Educational Services | $4,082,200 | $2,339,914 | 343 | N/A | Research |
| Cope Community Services INC | Health Care and Social Assistance | $4,019,700 | $4,078,729 | 356 | N/A | Research |
| Solar Industries, Inc. | Manufacturing | $4,013,590 | $4,058,894 | 442 | $438.4M | Research |
| Tucson Orthopaedic Institute PC | Health Care and Social Assistance | $3,844,395 | $3,887,431 | 282 | $88.5M | Research |
| Epidaurus | Health Care and Social Assistance | $3,757,900 | $3,802,682 | 352 | $59.9M | Research |
| Goodwill Industries of Southern Arizona, Inc. | Other Services (except Public Administration) | $3,414,000 | $3,453,565 | 312 | $59.6M | Research |
| Chapman Imports of Tucson, L.l.c. | Retail Trade | $3,395,800 | $0 | 276 | $69.6M | Research |
| Ke&g Construction, INC | Construction | $3,374,100 | $3,420,494 | 271 | $84.0M | Research |
| Visionquest National, Ltd. | Administrative and Support and Waste Management | $3,182,200 | $3,224,187 | 405 | $76.6M | Research |
| Hsl Cottonwood Rc Hotel, LLC | Accommodation and Food Services | $3,060,000 | $3,110,469 | 335 | $104.8M | Research |
| Dias Management INC | Accommodation and Food Services | $2,984,245 | $3,017,685 | 500 | $88.8M | Research |
| Rowe Enterprises INC | Retail Trade | $2,916,124 | $2,954,863 | 213 | $53.7M | Research |