| Ouachita Baptist University | Educational Services | $4,049,700 | $4,096,743 | 441 | N/A |  Research |
| Pharmacy Care of Arkansas, LLC | Retail Trade | $1,654,800 | $1,669,716 | 198 | $34.6M | Research |
| Wpm Community Pharmacies, LLC | Retail Trade | $1,607,200 | $1,617,812 | 210 | $36.6M | Research |
| Twin Rivers Health & Rehab, LLC | Health Care and Social Assistance | $940,600 | $951,243 | 131 | $22.3M | Research |
| Taylor King & Associates P.a. | Public Administration | $848,300 | $853,154 | 70 | N/A | Research |
| Taylor King and Associates PA | Professional, Scientific, and Technical Services | $827,444 | $833,765 | 78 | $19.0M | Research |
| Arkansas Counseling and Psychodiagnostics, Inc. | Health Care and Social Assistance | $667,500 | $675,163 | 90 | $14.6M | Research |
| South Central Arkansas Electric Cooperative, Inc. | Utilities | $644,500 | $649,691 | 29 | N/A | Research |
| Southwest Auto Group, LLC | Retail Trade | $617,500 | $624,572 | 59 | $14.9M | Research |
| Group Living, Inc. | Health Care and Social Assistance | $437,300 | $441,230 | 117 | N/A | Research |
| Charles Ledbetter Logging, INC | Agriculture, Forestry, Fishing and Hunting | $325,000 | $328,802 | 46 | <$5M | Research |
| K. W. Jester Logging INC | Agriculture, Forestry, Fishing and Hunting | $304,400 | $306,527 | 30 | <$5M | Research |
| K. W. Jester Logging, Inc. | Agriculture, Forestry, Fishing and Hunting | $304,400 | $307,185 | 30 | <$5M | Research |
| Shields Wood Products, INC | Manufacturing | $283,600 | $285,939 | 40 | $39.7M | Research |
| W.p. Malone, Inc. | Retail Trade | $228,000 | $229,505 | 20 | <$5M | Research |
| Allcare Specialty Pharmacy, LLC | Retail Trade | $194,200 | $195,913 | 19 | <$5M | Research |
| Hardman Lumber Co. of Arkadelphia, Inc. | Retail Trade | $183,100 | $184,459 | 27 | $5.6M | Research |
| Arkadelphia Clinic for Children and Young Adults P.a. | Health Care and Social Assistance | $179,782 | $180,446 | 24 | $7.5M | Research |
| Bray Family Medicine Pllc | Health Care and Social Assistance | $178,424 | $179,387 | 11 | <$5M | Research |
| Arkadelphia Clinic for Children and Young Adults, PA | Health Care and Social Assistance | $167,900 | $167,352 | 20 | $6.3M | Research |
| H&t Truss Mill INC | Manufacturing | $161,200 | $162,847 | 18 | $17.9M | Research |
| Bray Family Medicine Pllc | Health Care and Social Assistance | $159,900 | $161,876 | 15 | <$5M | Research |
| The Plaza at Twin Rivers, LLC | Health Care and Social Assistance | $153,900 | $155,662 | 30 | $5.1M | Research |
| Law Offices of Alan Levar Pllc | Professional, Scientific, and Technical Services | $151,000 | $152,820 | 18 | <$5M | Research |
| Southwest Sporting Goods Company Inc. | Retail Trade | $145,000 | $146,557 | 13 | <$5M | Research |