| Black INC | Retail Trade | $636,835 | $640,207 | 74 | $18.5M |  Research |
| Cormier Rice Mill | Manufacturing | $600,918 | $603,997 | 40 | $14.1M | Research |
| Heritage Agriculture of Arkansas at Dewitt, INC | Retail Trade | $159,989 | $161,602 | 24 | $5.6M | Research |
| Randall S Hestir DDS Inc. | Health Care and Social Assistance | $146,705 | $147,569 | 17 | <$5M | Research |
| Vansandt Farm Service LLC | Retail Trade | $137,489 | $138,171 | 13 | <$5M | Research |
| Vansandt Farm Services LLC | Retail Trade | $110,702 | $111,757 | 11 | <$5M | Research |
| Pfaffenberger Farms | Agriculture, Forestry, Fishing and Hunting | $91,669 | $92,214 | 6 | <$5M | Research |
| Wil-Co Flying Service L.l.c. | Agriculture, Forestry, Fishing and Hunting | $79,147 | $79,863 | 9 | <$5M | Research |
| Aufderheide Flying Service Inc. | Agriculture, Forestry, Fishing and Hunting | $73,163 | $73,746 | 10 | <$5M | Research |
| Menard Seed Company, Inc. | Wholesale Trade | $65,407 | $66,255 | 8 | <$5M | Research |
| Menard Seed Company Inc. | Wholesale Trade | $65,407 | $66,376 | 8 | <$5M | Research |
| Mark Hargrove and Joyce Hargrove | Agriculture, Forestry, Fishing and Hunting | $56,063 | $56,484 | 4 | <$5M | Research |
| Southern Ag Management LLC | Professional, Scientific, and Technical Services | $49,700 | $49,997 | 4 | <$5M | Research |
| Morton Farms Partnership | Agriculture, Forestry, Fishing and Hunting | $47,582 | $47,852 | 3 | <$5M | Research |
| Ameca of Dewitt INC | Accommodation and Food Services | $44,477 | $44,826 | 12 | <$5M | Research |
| Ameca of Dewitt INC | Accommodation and Food Services | $41,000 | $41,301 | 8 | <$5M | Research |
| Bigtime Rentals of Dewitt, Inc. | Real Estate and Rental and Leasing | $40,283 | $40,737 | 5 | <$5M | Research |
| Watkins Farms Partnership | Agriculture, Forestry, Fishing and Hunting | $38,479 | $38,690 | 2 | <$5M | Research |
| First Baptist Church of Dewitt | Other Services (except Public Administration) | $38,200 | $38,417 | 7 | <$5M | Research |
| Drew Counce Farm Ptr | Agriculture, Forestry, Fishing and Hunting | $36,695 | $36,931 | 5 | <$5M | Research |
| Crooked M Partnership | Agriculture, Forestry, Fishing and Hunting | $32,750 | $32,958 | 5 | <$5M | Research |
| First United Methodist Church of Dewitt | Other Services (except Public Administration) | $32,153 | $32,296 | 8 | N/A | Research |
| M. Jacobs Law Firm, Pllc | Professional, Scientific, and Technical Services | $31,696 | $32,008 | 2 | <$5M | Research |
| Adams Parts & Supplies Inc. | Retail Trade | $30,018 | $30,161 | 5 | <$5M | Research |
| W. and W. Foods, LLC | Accommodation and Food Services | $29,500 | $29,753 | 10 | <$5M | Research |