| Rainbow of Challenges, INC | Health Care and Social Assistance | $1,852,700 | $1,872,977 | 500 | N/A |  Research |
| Pafford Ems of Oklahoma, INC | Health Care and Social Assistance | $1,747,440 | $1,767,595 | 183 | $42.4M | Research |
| Steve Montgomery Co., Inc. | Accommodation and Food Services | $1,514,788 | $1,528,925 | 476 | $84.5M | Research |
| Pafford Medical Services, INC | Health Care and Social Assistance | $1,513,375 | $1,530,872 | 143 | $33.1M | Research |
| Pafford Medical Services of Mississippi, INC | Health Care and Social Assistance | $1,122,045 | $1,131,821 | 106 | $24.6M | Research |
| Pafford Medical Billing Services, INC | Health Care and Social Assistance | $949,833 | $960,737 | 120 | $27.8M | Research |
| Clv Enterprises, Inc. | Health Care and Social Assistance | $938,183 | $948,670 | 90 | $20.9M | Research |
| Smiles of Arkansas Dental Center Pllc | Health Care and Social Assistance | $541,900 | $545,864 | 52 | $12.0M | Research |
| Smiles of Arkansas Dental Center Pllc | Health Care and Social Assistance | $538,473 | $541,276 | 50 | $11.6M | Research |
| Divine Power LLC | Construction | $248,035 | $250,216 | 16 | <$5M | Research |
| Hope Auto Dealership INC | Retail Trade | $240,771 | $242,255 | 20 | $5.0M | Research |
| Hempstead County Farmers Association | Retail Trade | $195,000 | $196,250 | 33 | $6.8M | Research |
| Sls Trucking Inc. | Transportation and Warehousing | $192,583 | $193,532 | 25 | $5.0M | Research |
| Sls Trucking, Inc. | Transportation and Warehousing | $171,697 | $172,685 | 23 | <$5M | Research |
| Mclarty Butler Tate LLC | Retail Trade | $163,087 | $164,092 | 16 | <$5M | Research |
| Wend-Xx of Arkansas INC | Accommodation and Food Services | $146,900 | $147,871 | 45 | $8.0M | Research |
| Hospitality Inn of Hope Lp, Lllp | Accommodation and Food Services | $145,733 | $147,466 | 23 | $7.2M | Research |
| Hope Fire Extinguisher Service, INC | Construction | $144,086 | $145,148 | 24 | $7.9M | Research |
| P&t Land and Timber Co., LLC | Agriculture, Forestry, Fishing and Hunting | $133,065 | $29,673 | 9 | <$5M | Research |
| Ford and Ford INC | Wholesale Trade | $128,664 | $129,270 | 34 | $8.8M | Research |
| J&j Couriers LLC | Transportation and Warehousing | $128,012 | $128,622 | 13 | <$5M | Research |
| J & J Couriers, LLC | Transportation and Warehousing | $128,012 | $128,962 | 9 | <$5M | Research |
| Ford & Ford INC | Other Services (except Public Administration) | $127,647 | $128,560 | 34 | $6.5M | Research |
| Teyar LLC | Accommodation and Food Services | $127,093 | $127,797 | 23 | <$5M | Research |
| Anderson-Frazier Insurance Agency of Hope, Inc. | Retail Trade | $122,200 | $123,707 | 11 | <$5M | Research |