| Mena Hospital Commission | Health Care and Social Assistance | $2,644,059 | $2,673,805 | 303 | $60.1M | Research |
| Healthy Connections, Inc. | Health Care and Social Assistance | $1,814,500 | $1,825,363 | 191 | N/A | Research |
| Southwest Ems, INC | Health Care and Social Assistance | $1,035,185 | $1,045,254 | 111 | $25.7M | Research |
| Sterling Machinery INC | Manufacturing | $1,030,585 | $1,043,404 | 80 | $20.9M | Research |
| Sterling Machinery INC | Manufacturing | $943,097 | $947,341 | 69 | $18.1M | Research |
| Rich Mountain Electric Cooperative, INC | Utilities | $580,074 | $586,390 | 32 | N/A | Research |
| Rose Aircraft Services, INC | Transportation and Warehousing | $556,000 | $559,793 | 74 | $18.8M | Research |
| Brodix, INC | Manufacturing | $537,000 | $541,075 | 51 | $12.5M | Research |
| Rose Aircraft Services INC | Transportation and Warehousing | $519,000 | $524,801 | 71 | $18.0M | Research |
| Aviation Maintenance Services International, LLC | Transportation and Warehousing | $351,714 | $354,143 | 26 | <$5M | Research |
| Don's E-Z Pay, Inc. | Retail Trade | $332,396 | $335,433 | 46 | $8.3M | Research |
| Polk County Developmental Center INC | Other Services (except Public Administration) | $268,230 | $269,750 | 71 | N/A | Research |
| Polk County Developmental Center INC | Other Services (except Public Administration) | $267,917 | $269,785 | 73 | N/A | Research |
| Montco Mfg INC | Manufacturing | $209,955 | $211,387 | 40 | $10.5M | Research |
| Aleshire Electric INC | Construction | $202,327 | $203,063 | 24 | $7.9M | Research |
| Mountain View Clinic 1 LLC | Health Care and Social Assistance | $199,231 | $201,513 | 20 | $6.3M | Research |
| Freedom Pharmacy LLC | Professional, Scientific, and Technical Services | $188,461 | $190,376 | 29 | <$5M | Research |
| Papas Mexican Cafe LLC | Accommodation and Food Services | $171,714 | $172,668 | 22 | <$5M | Research |
| Mena Steel Buildings, Inc. | Construction | $169,800 | $171,083 | 22 | $25.1M | Research |
| Peachtree Mena LLC | Construction | $169,000 | $170,005 | 31 | $7.8M | Research |
| Rose-Wood Completions LLC | Transportation and Warehousing | $166,245 | $167,372 | 24 | <$5M | Research |
| Mena Steel Buildings Inc. | Construction | $159,835 | $160,838 | 22 | $25.1M | Research |
| Francis M. Dix Company, INC | Manufacturing | $156,000 | $157,500 | 22 | $5.8M | Research |
| J & J Womble Enterprises INC | Retail Trade | $125,926 | $126,937 | 32 | $8.0M | Research |
| Southern Disposal, Inc. | Administrative and Support and Waste Management | $125,000 | $125,932 | 25 | <$5M | Research |