| Piggott Community Hospital | Health Care and Social Assistance | $2,380,867 | $2,408,776 | 245 | N/A |  Research |
| General Baptist Nursing Home of Piggott | Health Care and Social Assistance | $256,448 | $259,750 | 52 | N/A | Research |
| General Baptist Nursing Home Board, Inc. | Health Care and Social Assistance | $252,710 | $255,978 | 12 | N/A | Research |
| Piggott Pharmacy LLC | Retail Trade | $122,793 | $0 | 13 | <$5M | Research |
| Scott Partnership | Agriculture, Forestry, Fishing and Hunting | $119,515 | $120,396 | 8 | <$5M | Research |
| Scott Partnership | Agriculture, Forestry, Fishing and Hunting | $107,836 | $108,704 | 8 | <$5M | Research |
| Mann Land Leveling LLC | Construction | $106,383 | $106,983 | 8 | <$5M | Research |
| Clay County Abstract & Title Ins | Real Estate and Rental and Leasing | $95,500 | $96,272 | 16 | <$5M | Research |
| Rainbow Land Leveling & Surveying LLC | Construction | $92,000 | $92,677 | 11 | <$5M | Research |
| Master Marketing | Wholesale Trade | $84,900 | $85,485 | 15 | <$5M | Research |
| General Baptist Assisted Living Facility | Health Care and Social Assistance | $82,305 | $83,347 | 15 | N/A | Research |
| Mcdougal Farms Gp | Agriculture, Forestry, Fishing and Hunting | $81,803 | $82,083 | 15 | <$5M | Research |
| Wb Russell Transportation, LLC | Transportation and Warehousing | $75,700 | $76,239 | 13 | <$5M | Research |
| Wb Russell Transportation LLC | Transportation and Warehousing | $75,700 | $76,092 | 13 | <$5M | Research |
| Sdi of Piggott, INC | Accommodation and Food Services | $70,700 | $71,222 | 32 | $5.7M | Research |
| Family Title INC | Professional, Scientific, and Technical Services | $69,378 | $54,614 | 4 | <$5M | Research |
| Mcdougal Farms Gp | Agriculture, Forestry, Fishing and Hunting | $66,885 | $67,217 | 11 | <$5M | Research |
| D & G Plumbing & Heating, Inc. | Retail Trade | $65,882 | $66,288 | 12 | <$5M | Research |
| Williams Farm and Landleveling LLC | Agriculture, Forestry, Fishing and Hunting | $63,240 | $63,585 | 6 | <$5M | Research |
| Mann Land Leveling, LLC | Construction | $63,000 | $63,483 | 6 | <$5M | Research |
| Jones and Sons Landleveling LLC | Construction | $62,800 | $63,180 | 11 | <$5M | Research |
| Mckenney Pharmacy LLC | Retail Trade | $61,200 | $61,535 | 7 | <$5M | Research |
| Kevin Murray | Agriculture, Forestry, Fishing and Hunting | $58,090 | $58,548 | 2 | <$5M | Research |
| Piggott Pharmacy LLC | Retail Trade | $49,768 | $77,535 | 8 | <$5M | Research |
| Pumpkin Hollow LLC | Agriculture, Forestry, Fishing and Hunting | $47,918 | $48,258 | 168 | $17.2M | Research |