| Cavenaugh Ford Co. | Retail Trade | $1,702,900 | $1,722,436 | 193 | $48.6M |  Research |
| Lawrence Memorial Health Foundation Inc. | Health Care and Social Assistance | $1,537,178 | $1,552,297 | 234 | $46.4M | Research |
| Farm Service, INC | Retail Trade | $1,339,703 | $1,349,639 | 109 | $22.5M | Research |
| Lawrence Hall Health & Rehabilitation | Health Care and Social Assistance | $1,141,168 | $1,152,392 | 220 | N/A | Research |
| Williams Baptist College | Educational Services | $959,500 | $965,444 | 200 | N/A | Research |
| Lawrence County Family Clinic, P.a. | Health Care and Social Assistance | $271,800 | $273,937 | 25 | $7.8M | Research |
| Arnold & Jacobs LLC | Agriculture, Forestry, Fishing and Hunting | $208,882 | $211,992 | 30 | <$5M | Research |
| Arnold & Jacobs LLC | Agriculture, Forestry, Fishing and Hunting | $196,546 | $212,950 | 37 | <$5M | Research |
| Castino Industries, Inc. | Manufacturing | $149,400 | $151,305 | 19 | $18.8M | Research |
| Castino Industries Inc. | Manufacturing | $148,400 | $149,699 | 19 | $18.8M | Research |
| Jon & Angela Rorex LLC | Accommodation and Food Services | $100,788 | $101,263 | 14 | <$5M | Research |
| T-Rex Ventures LLC | Manufacturing | $88,924 | $89,453 | 20 | $5.6M | Research |
| Industrial Metal Finishing INC | Other Services (except Public Administration) | $88,915 | $89,570 | 11 | <$5M | Research |
| Mcvay and Helms Veterinary Clinic | Professional, Scientific, and Technical Services | $88,501 | $89,192 | 11 | <$5M | Research |
| Naveera Pllc | Health Care and Social Assistance | $87,500 | $88,336 | 12 | <$5M | Research |
| Industrial Metal Finishing INC | Other Services (except Public Administration) | $84,883 | $85,845 | 10 | <$5M | Research |
| Clark General Contractors INC | Construction | $79,944 | $80,305 | 11 | $12.5M | Research |
| Clark General Contractors Inc. | Construction | $78,671 | $79,180 | 13 | $14.8M | Research |
| First Baptist Church of Walnut Ridge | Other Services (except Public Administration) | $77,944 | $78,503 | 22 | N/A | Research |
| Kidspot Walnut Ridge, Inc. | Health Care and Social Assistance | $76,600 | $77,217 | 18 | <$5M | Research |
| Jon & Angela Rorex LLC | Accommodation and Food Services | $71,991 | $72,565 | 26 | <$5M | Research |
| Naveera Pllc | Health Care and Social Assistance | $71,600 | $72,539 | 8 | <$5M | Research |
| Allied Ag Cat LLC | Retail Trade | $71,595 | $72,339 | 10 | <$5M | Research |
| Allied Ag Cat LLC | Retail Trade | $71,095 | $71,647 | 11 | <$5M | Research |
| Manus Welding LLC | Other Services (except Public Administration) | $68,309 | $68,890 | 15 | <$5M | Research |