| Northern Inyo Healthcare District | Health Care and Social Assistance | $4,381,095 | $9,042,586 | 499 | N/A |  Research |
| Toiyabe Indian Health Project INC | Health Care and Social Assistance | $2,098,125 | $2,226,163 | 160 | N/A | Research |
| Bishop Paiute Tribe Paiute Palace Casino | Arts, Entertainment, and Recreation | $1,274,890 | $1,289,246 | 203 | $28.4M | Research |
| Bishop Paiute Tribe Paiute Palace Casino | Arts, Entertainment, and Recreation | $1,157,182 | $1,167,581 | 137 | $19.2M | Research |
| Robbin Cromer-Tyler, Md, Inc. | Health Care and Social Assistance | $800,493 | $354,261 | 15 | <$5M | Research |
| High Country Lumber, Inc. | Retail Trade | $660,282 | $668,368 | 68 | $14.0M | Research |
| Erick Schats Bakkerij | Manufacturing | $537,378 | $548,478 | 55 | $19.4M | Research |
| Erick Schat's Bakkerij INC | Manufacturing | $537,378 | $544,459 | 71 | $25.1M | Research |
| Inyo-Mono Title Company | Real Estate and Rental and Leasing | $367,060 | $371,867 | 23 | <$5M | Research |
| Pioneer Home Health Care, Inc. | Health Care and Social Assistance | $343,706 | $294,570 | 34 | N/A | Research |
| Triad/holmes Associates | Professional, Scientific, and Technical Services | $307,011 | $310,367 | 22 | <$5M | Research |
| Dean's Plumbing & Heating, Inc. | Construction | $304,532 | $307,533 | 24 | $7.6M | Research |
| Meadow Farms Country Smoke House Inc. | Accommodation and Food Services | $286,408 | $289,131 | 30 | $5.3M | Research |
| Mountain Rambler Brewery, INC | Accommodation and Food Services | $274,901 | $277,484 | 28 | <$5M | Research |
| Bishop Veterinary Hospital, Inc. | Professional, Scientific, and Technical Services | $273,925 | $267,107 | 44 | $6.2M | Research |
| Sabrina Enterprises | Retail Trade | $273,340 | $276,515 | 36 | $6.3M | Research |
| J Rousek Toy Co INC | Retail Trade | $267,728 | $271,395 | 31 | $7.7M | Research |
| Perry Motors, Inc. | Retail Trade | $255,124 | $256,745 | 27 | $6.8M | Research |
| Kdi Hospitality INC | Accommodation and Food Services | $241,200 | $32,796 | 5 | <$5M | Research |
| Manor Market INC | Retail Trade | $232,998 | $235,507 | 45 | $11.2M | Research |
| V & V Motors, Inc. DBA Bishop Ford | Wholesale Trade | $216,530 | $0 | 20 | $6.1M | Research |
| Looney Bean Bishop | Accommodation and Food Services | $210,000 | $212,112 | 24 | <$5M | Research |
| Robert Beach & Associates Insurance Agency, Inc. | Finance and Insurance | $205,468 | $206,569 | 17 | $8.7M | Research |
| Meadow Farms Country Smoke House, Inc. | Accommodation and Food Services | $204,500 | $206,651 | 30 | $5.3M | Research |
| V&v Motors Inc. | Retail Trade | $199,168 | $200,821 | 18 | <$5M | Research |