| Wind & Sea Restaurants INC | Accommodation and Food Services | $2,000,000 | $2,009,315 | 215 | $38.2M |  Research |
| Wind & Sea Restaurants, INC | Accommodation and Food Services | $1,744,500 | $1,761,180 | 249 | $44.2M | Research |
| Optivest Properties LLC | Real Estate and Rental and Leasing | $1,362,500 | $203,326 | 197 | $29.6M | Research |
| St. Edward the Confessor School | Other Services (except Public Administration) | $1,057,765 | $1,064,720 | 141 | N/A | Research |
| Truthmd, LLC | Professional, Scientific, and Technical Services | $1,016,672 | $1,022,182 | 48 | $9.9M | Research |
| Watermark Sea Bluffs, LLC | Health Care and Social Assistance | $781,700 | $792,451 | 166 | $28.2M | Research |
| Aliso Electric Inc. | Construction | $778,912 | $787,277 | 85 | $28.0M | Research |
| Jfat Dana Point LLC DBA Jimmy's Famous American Tavern | Accommodation and Food Services | $741,845 | $748,511 | 22 | <$5M | Research |
| Ocean Institute | Educational Services | $692,000 | $700,001 | 127 | $16.5M | Research |
| Ocean Institute | Educational Services | $692,000 | $698,048 | 47 | $6.1M | Research |
| Coastal Restaurant Group INC | Accommodation and Food Services | $669,715 | $673,146 | 25 | <$5M | Research |
| Ocean Hills Recovery INC | Health Care and Social Assistance | $628,534 | $631,764 | 54 | $9.2M | Research |
| Dana Point Harbor Grill INC | Accommodation and Food Services | $617,057 | $619,677 | 57 | $10.1M | Research |
| Noble Pursuit LLC | Accommodation and Food Services | $549,400 | $554,442 | 114 | $20.2M | Research |
| Jfat Dana Point LLC | Accommodation and Food Services | $521,800 | $526,146 | 90 | $16.0M | Research |
| Ocean Hills Recovery INC | Health Care and Social Assistance | $502,372 | $505,683 | 51 | $9.1M | Research |
| Pacific Asian Enterprises, Inc. | Manufacturing | $500,525 | $504,954 | 37 | $9.7M | Research |
| Panoramic Software Corp. | Professional, Scientific, and Technical Services | $488,700 | $493,132 | 21 | <$5M | Research |
| Coastal Restaurant Group INC | Accommodation and Food Services | $478,645 | $480,857 | 66 | $11.7M | Research |
| Panoramic Software Corporation | Professional, Scientific, and Technical Services | $462,274 | $466,757 | 24 | <$5M | Research |
| Dana Point Harbor Grill INC | Accommodation and Food Services | $440,755 | $443,653 | 57 | $10.1M | Research |
| Qrs, LLC | Administrative and Support and Waste Management | $438,717 | $441,460 | 45 | $7.1M | Research |
| Summers, Murphy & Partners, Inc. | Professional, Scientific, and Technical Services | $412,675 | $417,797 | 30 | $6.0M | Research |
| St. Edward the Confessor Catholic Church | Other Services (except Public Administration) | $402,445 | $405,102 | 69 | N/A | Research |
| Inspectre Solutions | Administrative and Support and Waste Management | $340,760 | $344,962 | 29 | $5.5M | Research |