| Communicare Health Centers | Health Care and Social Assistance | $3,948,660 | $3,989,792 | 98 | N/A | Research |
| D. G. Smith Enterprises INC | Accommodation and Food Services | $3,338,100 | $3,376,511 | 500 | $88.8M | Research |
| West Yost & Associates, Inc. | Professional, Scientific, and Technical Services | $2,664,385 | $2,694,920 | 183 | $22.6M | Research |
| Golden Arch Enterprises, Inc. | Accommodation and Food Services | $2,330,900 | $2,356,955 | 483 | $85.8M | Research |
| Veterinary Information Network, INC | Information | $2,222,985 | $1,944,939 | 160 | $26.9M | Research |
| Marrone Bio Innovations | Manufacturing | $1,723,000 | $1,732,668 | 155 | $153.7M | Research |
| Mi5 Incorporated | Accommodation and Food Services | $1,403,605 | $1,420,833 | 245 | $43.5M | Research |
| Far Western Anthropological Research Group, Inc. | Professional, Scientific, and Technical Services | $1,367,684 | $1,383,564 | 86 | $12.0M | Research |
| Dkd of Davis, Inc. | Retail Trade | $1,301,375 | $1,315,439 | 97 | $24.4M | Research |
| Sierra Railroad Company | Transportation and Warehousing | $1,200,592 | $1,214,678 | 77 | $19.5M | Research |
| Tandem Properties, Inc, | Real Estate and Rental and Leasing | $1,180,015 | $1,188,996 | 82 | $12.3M | Research |
| Engage3 INC | Manufacturing | $1,169,000 | $955,880 | 74 | $19.4M | Research |
| Arcadia Biosciences, Inc. | Professional, Scientific, and Technical Services | $1,107,700 | $1,122,315 | 75 | $15.6M | Research |
| Larry Walker Associates, Inc. | Professional, Scientific, and Technical Services | $1,096,067 | $1,107,758 | 49 | $5.1M | Research |
| Mi5 INC | Accommodation and Food Services | $1,002,500 | $1,011,646 | 275 | $48.8M | Research |
| Yolo Hospice, INC | Other Services (except Public Administration) | $991,559 | $998,362 | 61 | N/A | Research |
| Sierra Railroad Company | Transportation and Warehousing | $985,450 | $998,327 | 109 | $27.6M | Research |
| Shottenkirk-Davis, LLC | Retail Trade | $984,700 | $996,004 | 78 | $19.7M | Research |
| Evolve Biosystems, Inc. | Accommodation and Food Services | $927,045 | $938,424 | 43 | $13.4M | Research |
| Davis Food Cooperative, INC | Retail Trade | $831,700 | $845,440 | 120 | $30.0M | Research |
| Colmax LLC | Accommodation and Food Services | $808,042 | $816,210 | 94 | $16.7M | Research |
| Resource Management Associates, Inc. | Professional, Scientific, and Technical Services | $726,722 | $730,598 | 31 | <$5M | Research |
| Agrinos Inc. | Manufacturing | $705,293 | $671,987 | 37 | $36.7M | Research |
| Colmax, LLC | Accommodation and Food Services | $577,620 | $582,241 | 116 | $20.6M | Research |
| Leehan of Davis Inc. | Retail Trade | $575,125 | $578,945 | 26 | $6.6M | Research |