| Producers Dairy Foods Inc. | Manufacturing | $10,000,000 | $10,115,278 | 500 | $176.5M |  Research |
| Sweetwood Farm Inc. | Agriculture, Forestry, Fishing and Hunting | $8,432,495 | $539,322 | 271 | $27.7M | Research |
| Saladino's, Inc. | Wholesale Trade | $6,539,700 | $6,607,964 | 448 | $115.3M | Research |
| Diocese of Fresno Education Corporation | Construction | $6,101,500 | $6,174,887 | 498 | N/A | Research |
| Exclusive Wireless, Inc. | Real Estate and Rental and Leasing | $5,416,000 | $5,295,396 | 500 | $75.0M | Research |
| Electronic Recyclers International Inc. | Administrative and Support and Waste Management | $4,439,700 | $4,495,690 | 437 | $82.7M | Research |
| Sante Health System Inc. | Health Care and Social Assistance | $4,300,987 | $4,242,711 | 397 | $124.6M | Research |
| Fresno Plumbing and Heating INC | Construction | $4,282,252 | $4,337,445 | 375 | $118.6M | Research |
| Scelzi Enterprises, INC | Manufacturing | $4,278,200 | $4,326,960 | 431 | $112.8M | Research |
| Kings View | Health Care and Social Assistance | $4,230,830 | $3,845,038 | 420 | N/A | Research |
| Roman Catholic Bishop of Fresno | Other Services (except Public Administration) | $3,949,600 | $4,003,358 | 433 | N/A | Research |
| Mccormick, Barstow, Sheppard, Wayte & Carruth, LLP | Professional, Scientific, and Technical Services | $3,928,565 | $3,973,198 | 233 | $56.6M | Research |
| Neya INC | Retail Trade | $3,750,000 | $37,722 | 6 | <$5M | Research |
| Community Medical Providers Medical Group, Inc. | Health Care and Social Assistance | $3,709,772 | $3,759,236 | 297 | $93.2M | Research |
| Betts Company | Manufacturing | $3,200,000 | $3,242,684 | 235 | $57.4M | Research |
| Michael Cadillac Inc. | Retail Trade | $3,145,293 | $1,925,090 | 260 | $65.5M | Research |
| Four Seasons Contracting | Professional, Scientific, and Technical Services | $3,137,500 | $3,188,302 | 413 | $42.7M | Research |
| Lozano Smith LLP | Professional, Scientific, and Technical Services | $3,087,647 | $0 | 178 | $43.3M | Research |
| Fresno Beverage Company Inc. | Wholesale Trade | $3,000,000 | $3,034,953 | 276 | $71.0M | Research |
| Penny Newman Grain Company | Wholesale Trade | $2,975,200 | $3,008,946 | 190 | $48.9M | Research |
| La Tapatia Tortilleria, Inc. | Manufacturing | $2,968,784 | $1,500,413 | 149 | $52.6M | Research |
| Zim Industries, INC | Construction | $2,932,600 | $2,972,027 | 166 | $51.5M | Research |
| Westside Ag. Ii, Inc. | Professional, Scientific, and Technical Services | $2,915,270 | $2,975,253 | 467 | $65.4M | Research |
| Sierra Pacific Orthopaedic Center | Health Care and Social Assistance | $2,901,300 | $2,934,208 | 221 | $69.4M | Research |
| James Mckoane Enterprises INC | Retail Trade | $2,819,559 | $2,860,269 | 269 | $67.8M | Research |