| Asc Staffing Group, LLC | Administrative and Support and Waste Management | $9,302,500 | $9,410,974 | 500 | $78.7M |  Research |
| Host Healthcare, Inc. | Administrative and Support and Waste Management | $8,110,000 | $8,201,238 | 485 | $76.3M | Research |
| La Jolla Institute for Immunology | Health Care and Social Assistance | $6,146,100 | $5,831,602 | 376 | N/A | Research |
| Mobileone, LLC | Retail Trade | $6,036,800 | $6,102,957 | 500 | $153.1M | Research |
| Tyson & Mendes, LLP | Professional, Scientific, and Technical Services | $5,498,500 | $5,560,565 | 278 | $67.6M | Research |
| La Jolla Country Day School | Educational Services | $4,351,900 | $0 | 227 | N/A | Research |
| La Jolla Beach and Tennis Club Partners, L.p. | Arts, Entertainment, and Recreation | $4,200,165 | $4,262,117 | 365 | $51.1M | Research |
| Burger Lounge of America, LLC | Accommodation and Food Services | $3,687,858 | $3,728,273 | 246 | $43.7M | Research |
| J Craig Venter Institute INC | Professional, Scientific, and Technical Services | $3,044,861 | $3,078,063 | 151 | N/A | Research |
| Boffo Cinemas LLC | Information | $2,539,427 | $2,387,260 | 415 | $69.7M | Research |
| Western States Asset Management, Inc. | Real Estate and Rental and Leasing | $2,396,300 | $2,344,606 | 202 | $30.3M | Research |
| Boffo Cinemas LLC | Information | $2,000,000 | $2,022,159 | 286 | $48.0M | Research |
| George's at the Cove INC | Accommodation and Food Services | $2,000,000 | $2,018,466 | 84 | $14.9M | Research |
| J Craig Venture Institute Duplicate | Professional, Scientific, and Technical Services | $2,000,000 | $2,018,278 | 129 | N/A | Research |
| La Jolla Beach and Tennis Club Partners L.p. | Arts, Entertainment, and Recreation | $2,000,000 | $2,024,500 | 217 | $30.4M | Research |
| Sammys Woodfired Pizza | Accommodation and Food Services | $2,000,000 | $2,012,167 | 297 | $52.7M | Research |
| Inhibrx INC | Professional, Scientific, and Technical Services | $1,875,460 | $0 | 92 | $19.1M | Research |
| Theater and Arts Foundation | Arts, Entertainment, and Recreation | $1,793,257 | $1,820,426 | 119 | $19.5M | Research |
| Sammy's Woodfired Pizza | Accommodation and Food Services | $1,625,000 | $1,633,976 | 400 | $71.0M | Research |
| George's at the Cove, INC | Accommodation and Food Services | $1,524,900 | $1,533,946 | 175 | $31.1M | Research |
| Lawrence Family Jewish Community Centers | Health Care and Social Assistance | $1,524,600 | $1,536,797 | 135 | $21.9M | Research |
| United Support Services, Inc. | Professional, Scientific, and Technical Services | $1,500,155 | $1,517,470 | 132 | $27.3M | Research |
| Coi Pharmaceuticals, INC | Professional, Scientific, and Technical Services | $1,448,085 | $0 | 62 | $12.9M | Research |
| Lawrence Family Jewish Community Centers | Educational Services | $1,445,800 | $1,460,496 | 194 | $25.9M | Research |
| Ambrx, Inc. | Manufacturing | $1,338,749 | $0 | 58 | $57.5M | Research |