| Fuzion Field Services LLC | Administrative and Support and Waste Management | $1,652,318 | $1,674,119 | 95 | $18.0M |  Research |
| Kit Carson County Health Service District | Health Care and Social Assistance | $1,377,755 | $1,390,538 | 137 | N/A | Research |
| 5 Star Feedlot INC | Agriculture, Forestry, Fishing and Hunting | $452,242 | $454,692 | 44 | $7.2M | Research |
| 5 Star Feedlot, INC | Agriculture, Forestry, Fishing and Hunting | $452,242 | $457,330 | 44 | $7.2M | Research |
| Hitchcock Incorporated | Manufacturing | $434,494 | $437,137 | 39 | $10.2M | Research |
| Burlington Feeders, Inc. | Agriculture, Forestry, Fishing and Hunting | $408,630 | $411,138 | 44 | $7.2M | Research |
| Madison Senior Living Management, LLC | Health Care and Social Assistance | $346,400 | $351,117 | 51 | $8.7M | Research |
| Eastern Colorado Seeds LLC | Wholesale Trade | $300,191 | $302,124 | 21 | $5.4M | Research |
| Country Boy Productions Ltd | Accommodation and Food Services | $282,731 | $284,663 | 26 | <$5M | Research |
| Eastern Colorado Seeds, LLC | Agriculture, Forestry, Fishing and Hunting | $250,314 | $251,671 | 18 | <$5M | Research |
| Cure Brothers | Agriculture, Forestry, Fishing and Hunting | $238,446 | $240,029 | 19 | <$5M | Research |
| Cure Brothers | Agriculture, Forestry, Fishing and Hunting | $238,446 | $240,048 | 11 | <$5M | Research |
| Dynamic Dimensions Inc. | Health Care and Social Assistance | $238,023 | $239,279 | 27 | N/A | Research |
| Adept Concrete Ltd. | Construction | $224,492 | $227,069 | 27 | $6.2M | Research |
| Duerst Machine Works | Other Services (except Public Administration) | $224,432 | $225,722 | 15 | <$5M | Research |
| Vince's Chevrolet Buick Gmc Cadillac Inc. | Retail Trade | $213,231 | $214,434 | 22 | $5.5M | Research |
| Country Boy Productions | Accommodation and Food Services | $201,950 | $203,106 | 28 | <$5M | Research |
| The Bank of Burlington | Management of Companies and Enterprises | $200,161 | $0 | 16 | <$5M | Research |
| Schaal Drilling LLC | Construction | $180,871 | $182,388 | 13 | <$5M | Research |
| Schaal Drilling, LLC | Construction | $180,871 | $181,747 | 13 | <$5M | Research |
| Codell Well Service, LLC | Mining, Quarrying, and Oil and Gas Extraction | $179,939 | $181,063 | 14 | <$5M | Research |
| Halde Sand & Gravel, Inc. | Mining, Quarrying, and Oil and Gas Extraction | $157,420 | $158,373 | 12 | <$5M | Research |
| Codell Well Service LLC | Mining, Quarrying, and Oil and Gas Extraction | $144,943 | $146,202 | 11 | <$5M | Research |
| Atlas Farms LLC | Agriculture, Forestry, Fishing and Hunting | $129,430 | $130,494 | 7 | <$5M | Research |
| H&h Lumber, LLC | Retail Trade | $124,482 | $125,614 | 14 | <$5M | Research |