| Madwire, LLC | Information | $6,267,100 | $6,340,390 | 500 | $84.0M |  Research |
| Orthopaedic & Spine Center of the Rockies, PC | Health Care and Social Assistance | $5,911,237 | $5,974,783 | 447 | $140.3M | Research |
| Associates in Family Medicine, P.c. | Health Care and Social Assistance | $4,797,509 | $4,572,885 | 349 | $109.5M | Research |
| Employment Solutions Personnel Services, Inc. | Administrative and Support and Waste Management | $3,789,075 | $3,835,070 | 467 | $73.5M | Research |
| The Eye Center of Northern Colorado, PC | Health Care and Social Assistance | $3,716,229 | $3,759,585 | 300 | $94.2M | Research |
| Summitstone Health Partners | Health Care and Social Assistance | $3,703,749 | $3,752,824 | 298 | N/A | Research |
| Landmark Event Staffing Services, Inc. | Arts, Entertainment, and Recreation | $3,251,000 | $829,071 | 500 | $82.0M | Research |
| Northern Colorado Anesthesia Professionals, Pllc | Health Care and Social Assistance | $3,078,500 | $3,110,954 | 108 | $33.9M | Research |
| Rio Grande Mexican Restaurants Inc. | Accommodation and Food Services | $2,881,400 | $2,915,096 | 427 | $52.3M | Research |
| Gallegos Sanitation, INC | Administrative and Support and Waste Management | $2,774,300 | $2,807,052 | 238 | $45.0M | Research |
| In-Situ INC | Manufacturing | $2,765,927 | $2,798,304 | 175 | $45.8M | Research |
| The Neenan Company Lllp | Professional, Scientific, and Technical Services | $2,548,400 | $2,581,812 | 141 | $43.7M | Research |
| Emergency Physicians of the Rockies | Health Care and Social Assistance | $2,499,262 | $2,528,420 | 79 | $24.8M | Research |
| Brinkman Construction, Inc. | Construction | $2,461,470 | $2,490,187 | 147 | $167.5M | Research |
| Phase II Company, INC | Construction | $2,327,200 | $2,354,157 | 157 | $39.7M | Research |
| Dellenbach Chevrolet, Inc. | Retail Trade | $2,107,045 | $2,131,452 | 180 | $45.4M | Research |
| Walker Manufacturing Company | Manufacturing | $2,063,505 | $2,087,080 | 170 | $44.5M | Research |
| Canidium | Professional, Scientific, and Technical Services | $2,000,000 | $2,013,556 | 100 | $20.7M | Research |
| Landmark Event Staffing Services Inc. | Administrative and Support and Waste Management | $2,000,000 | $2,012,889 | 234 | $34.3M | Research |
| Rio Grande Mexican Restaurants INC | Accommodation and Food Services | $2,000,000 | $2,015,056 | 300 | $53.3M | Research |
| Odell Brewing Company, Inc. | Manufacturing | $1,998,853 | $2,019,952 | 140 | $49.4M | Research |
| Spirit Hospitality II LLC | Accommodation and Food Services | $1,994,042 | $2,005,397 | 175 | $54.7M | Research |
| Air Comfort, Inc. | Construction | $1,971,800 | $1,693,711 | 145 | $45.9M | Research |
| Markley Motors, Inc. | Retail Trade | $1,946,105 | $1,900,130 | 147 | $37.0M | Research |
| Canidium LLC | Professional, Scientific, and Technical Services | $1,931,800 | $1,950,259 | 120 | $24.8M | Research |