| Bethany Nursing & Rehab Center | Health Care and Social Assistance | $1,549,000 | $1,567,029 | 190 | $32.3M | Research |
| Rmh Group INC | Professional, Scientific, and Technical Services | $1,514,724 | $1,526,095 | 69 | $8.5M | Research |
| Harrison Western Construction Corporation, Inc. | Construction | $1,451,700 | $1,461,781 | 67 | $20.8M | Research |
| Homesphere LLC | Professional, Scientific, and Technical Services | $1,288,700 | $1,302,339 | 53 | $7.4M | Research |
| Anne Holland Ventures INC | Professional, Scientific, and Technical Services | $1,283,100 | $1,296,145 | 82 | $9.2M | Research |
| Adc Management Services INC | Administrative and Support and Waste Management | $1,257,700 | $1,261,788 | 185 | $29.1M | Research |
| Critical Care, Pulmonary and Sleep Associates, Professional | Health Care and Social Assistance | $1,255,545 | $1,267,682 | 67 | $21.0M | Research |
| Multispecialty Physician Partners, LLC | Health Care and Social Assistance | $1,232,712 | $1,248,517 | 88 | $16.1M | Research |
| Easter Seals Colorado | Other Services (except Public Administration) | $1,120,600 | $1,129,411 | 220 | $42.0M | Research |
| Easter Seals Colorado | Other Services (except Public Administration) | $1,118,477 | $1,128,497 | 122 | $23.3M | Research |
| Lexicon Care, Inc. | Health Care and Social Assistance | $1,049,200 | $1,062,490 | 130 | $22.1M | Research |
| Denver Eye Surgeon, PC | Health Care and Social Assistance | $1,048,600 | $1,057,630 | 76 | $15.1M | Research |
| Denver Eye Surgeons PC | Health Care and Social Assistance | $1,048,600 | $1,058,766 | 101 | $20.0M | Research |
| Fred Emich Iii, INC | Retail Trade | $1,040,200 | $1,049,475 | 103 | $26.0M | Research |
| American Truck Business Services, LLC | Transportation and Warehousing | $1,035,700 | $1,041,801 | 120 | $8.3M | Research |
| Colorado Heart and Vascular PC | Health Care and Social Assistance | $1,027,900 | $1,034,010 | 76 | $23.9M | Research |
| Computronix USA INC | Professional, Scientific, and Technical Services | $1,024,064 | $1,038,794 | 51 | $10.5M | Research |
| Neptune and Company, Incorporated | Professional, Scientific, and Technical Services | $1,023,590 | $1,036,547 | 500 | $51.8M | Research |
| Pinyon Environmental INC | Professional, Scientific, and Technical Services | $1,008,780 | $1,021,825 | 60 | $7.4M | Research |
| Quicksilver Express Courier of Colorado, Inc. | Transportation and Warehousing | $940,000 | $949,786 | 107 | $29.4M | Research |
| Elward Systems Corporation | Manufacturing | $930,875 | $936,331 | 54 | $13.2M | Research |
| Elward Systems Corporation | Manufacturing | $930,800 | $937,652 | 53 | $13.0M | Research |
| Blueprint Action LLC | Administrative and Support and Waste Management | $922,334 | $929,586 | 125 | $23.6M | Research |
| Sunshine Building Maintenance INC | Administrative and Support and Waste Management | $916,963 | $927,389 | 250 | $54.2M | Research |
| Asr Companies Inc. | Construction | $903,300 | $908,670 | 61 | $19.3M | Research |