| Spanish Peaks Healthcare Systems | Health Care and Social Assistance | $6,000,000 | $6,082,685 | 395 | N/A |  Research |
| Big R Holdings, INC | Retail Trade | $3,820,223 | $3,863,837 | 500 | $103.2M | Research |
| Industrial Constructors/managers Inc. | Construction | $3,016,219 | $3,050,067 | 202 | $230.1M | Research |
| Sangre De Cristo Hospice and Pallative Care | Health Care and Social Assistance | $2,246,702 | $1,881,389 | 251 | N/A | Research |
| Crossroads' Turning Points, Inc. | Health Care and Social Assistance | $2,133,200 | $2,161,837 | 235 | N/A | Research |
| Whole Hemp Company LLC | Wholesale Trade | $2,000,000 | $0 | 200 | $51.5M | Research |
| Rocky Mountain Eye Center Inc. a Colorado Provider Network | Health Care and Social Assistance | $1,876,297 | $1,887,092 | 165 | $51.8M | Research |
| Rocky Mountain Eye Center, Inc. a Colorado Provider Network | Health Care and Social Assistance | $1,876,296 | $1,896,396 | 164 | $51.5M | Research |
| Main Electric, Ltd. | Construction | $1,743,834 | $1,760,110 | 75 | $24.7M | Research |
| Southern Colorado Clinic P.c. | Health Care and Social Assistance | $1,685,900 | $1,695,230 | 138 | $43.3M | Research |
| Dale Spradley Motors, Inc. | Retail Trade | $1,630,900 | $1,642,061 | 145 | $36.5M | Research |
| San Isabel Electric Association, INC | Utilities | $1,602,037 | $1,616,945 | 74 | N/A | Research |
| 271 Lake Davis Holding, LLC | Agriculture, Forestry, Fishing and Hunting | $1,301,470 | $812,320 | 72 | $7.4M | Research |
| Blazer Electric Supply Management | Wholesale Trade | $1,258,690 | $1,269,725 | 96 | $29.4M | Research |
| T R Toppers, Inc. | Wholesale Trade | $1,253,800 | $1,261,907 | 100 | $25.7M | Research |
| The Center at Park West LLC | Health Care and Social Assistance | $1,184,058 | $1,191,097 | 228 | $38.8M | Research |
| Summit Education Group | Administrative and Support and Waste Management | $1,145,608 | $1,161,898 | 112 | $21.2M | Research |
| Center at Parkwest LLC | Health Care and Social Assistance | $1,098,700 | $1,194,023 | 116 | $19.7M | Research |
| Chavez Huerta Preparatory Academy | Educational Services | $1,084,827 | $1,093,506 | 124 | N/A | Research |
| Southern Colorado Emergency Medicine Associates P.c. | Health Care and Social Assistance | $1,015,407 | $1,020,851 | 62 | $10.0M | Research |
| Pueblo Electrics Inc. | Construction | $954,000 | $959,332 | 65 | $21.4M | Research |
| Pueblo Electrics INC | Construction | $953,046 | $960,174 | 61 | $20.1M | Research |
| Pueblo Diversified Industries, | Health Care and Social Assistance | $931,700 | $937,699 | 202 | $32.7M | Research |
| Southwest Motors, INC | Retail Trade | $930,200 | $936,272 | 59 | $14.9M | Research |
| T & T Electric Co. INC | Construction | $916,013 | $921,152 | 41 | $13.5M | Research |