| Willimantic Waste Paper Co., Inc. | Wholesale Trade | $3,353,880 | $3,393,024 | 320 | $98.0M |  Research |
| Generations Family Health Center, Inc. | Health Care and Social Assistance | $3,000,000 | $3,061,216 | 207 | N/A | Research |
| Anesthesia Associates of Willimantic | Health Care and Social Assistance | $1,441,400 | $1,458,381 | 72 | $22.6M | Research |
| Anesthesia Associates of Willimantic PC | Health Care and Social Assistance | $1,441,400 | $1,451,707 | 60 | $18.8M | Research |
| Northeast Emergency Medicine Specialists LLC | Health Care and Social Assistance | $1,418,098 | $1,433,618 | 41 | $12.9M | Research |
| Northeast Emergency Medicine Specialists, LLC | Manufacturing | $1,418,097 | $1,433,736 | 54 | $53.6M | Research |
| Jacc Healthcare Center of Windham LLC | Health Care and Social Assistance | $1,311,600 | $1,328,633 | 133 | $22.6M | Research |
| Perception Programs, Inc. | Health Care and Social Assistance | $1,010,000 | $1,010,548 | 1 | <$5M | Research |
| Capitol Garage INC | Retail Trade | $640,700 | $649,073 | 47 | $11.8M | Research |
| Temporaries of New England, Inc. | Administrative and Support and Waste Management | $608,200 | $603,772 | 150 | $23.6M | Research |
| Temporaries of New England Inc. | Administrative and Support and Waste Management | $527,650 | $532,739 | 141 | $22.2M | Research |
| Para-Pharm, Inc. | Manufacturing | $520,570 | $524,692 | 39 | $38.7M | Research |
| Willimantic Brewing Company LLC | Accommodation and Food Services | $500,000 | $503,375 | 68 | $12.1M | Research |
| Center for Medicare Advocacy INC | Finance and Insurance | $489,700 | $493,537 | 29 | N/A | Research |
| Gem Chevrolet Inc. | Retail Trade | $441,700 | $388,193 | 35 | $8.8M | Research |
| Connecticut Dental Groups PC | Other Services (except Public Administration) | $412,198 | $415,270 | 32 | $6.1M | Research |
| Windham Materials, LLC | Manufacturing | $409,575 | $414,254 | 25 | $24.8M | Research |
| Builders Concrete East LLC | Manufacturing | $409,575 | $845,962 | 57 | $56.5M | Research |
| Eastern Connecticut Ear, Nose & Throat PC | Health Care and Social Assistance | $353,900 | $357,216 | 30 | $9.4M | Research |
| Eastern Connecticut Ear Nose & Throat PC | Health Care and Social Assistance | $352,547 | $356,111 | 29 | $9.1M | Research |
| Companions & Homemakers by Nancy and Hazel | Health Care and Social Assistance | $253,952 | $255,691 | 107 | $17.3M | Research |
| Willimantic Brewing Company LLC | Accommodation and Food Services | $250,000 | $252,222 | 82 | $14.6M | Research |
| Mackeys INC | Retail Trade | $248,400 | $250,156 | 35 | $7.2M | Research |
| Willimantic Food Coop | Retail Trade | $243,440 | $245,604 | 30 | $7.5M | Research |
| Northeast Recyclers of Widham INC | Manufacturing | $240,100 | $242,264 | 19 | <$5M | Research |