| Floyd a Megee Motors Inc. | Retail Trade | $348,200 | $350,415 | 31 | $7.8M |  Research |
| Sea Care LLC | Health Care and Social Assistance | $331,640 | $333,330 | 61 | $10.4M | Research |
| Sussex Eye Center, P.a. | Health Care and Social Assistance | $329,180 | $332,273 | 32 | $7.5M | Research |
| Premier Orthopaedic Bone & Joint Care | Health Care and Social Assistance | $288,105 | $292,091 | 29 | $9.1M | Research |
| Builders Supply of Delmarva, Inc. | Retail Trade | $287,015 | $289,024 | 27 | $5.6M | Research |
| Davis & Adams | Accommodation and Food Services | $278,842 | $281,692 | 86 | $15.3M | Research |
| Sussex Pain Relief Center LLC | Health Care and Social Assistance | $273,187 | $275,243 | 20 | $6.3M | Research |
| J.g. Townsend, Jr., & Co. | Construction | $272,731 | $275,077 | 18 | $5.6M | Research |
| Tpi Partners, INC | Manufacturing | $271,800 | $273,751 | 28 | $27.8M | Research |
| Mulligans Pointe LLC | Accommodation and Food Services | $256,211 | $257,699 | 50 | $8.9M | Research |
| Justin Tanks, LLC | Manufacturing | $250,900 | $254,509 | 22 | $21.8M | Research |
| Crossroad Community Church Inc. | Other Services (except Public Administration) | $240,542 | $0 | 18 | N/A | Research |
| Tess INC | Other Services (except Public Administration) | $236,394 | $237,977 | 16 | <$5M | Research |
| Tpi Partners INC | Manufacturing | $230,740 | $233,749 | 38 | $37.7M | Research |
| Golden Georgetown LLC | Accommodation and Food Services | $230,257 | $232,892 | 2 | <$5M | Research |
| Service Quest Staffing Corporation | Administrative and Support and Waste Management | $221,600 | $208,030 | 25 | <$5M | Research |
| Fuqua, Willard, Stevens & Schab, P.a. | Professional, Scientific, and Technical Services | $220,200 | $221,660 | 22 | $5.3M | Research |
| Moore & Rutt P.a. | Professional, Scientific, and Technical Services | $219,223 | $221,141 | 15 | <$5M | Research |
| M.l. Joseph Sand & Gravel Co., Inc. | Mining, Quarrying, and Oil and Gas Extraction | $216,760 | $218,435 | 18 | N/A | Research |
| Creative Floors South, INC | Construction | $216,000 | $217,687 | 13 | <$5M | Research |
| Sussex Pain Relief Center, LLC | Health Care and Social Assistance | $201,787 | $203,664 | 20 | $5.4M | Research |
| Davis & Adams LLC | Accommodation and Food Services | $199,172 | $201,728 | 86 | $15.3M | Research |
| Solutions Ipem, LLC | Professional, Scientific, and Technical Services | $197,875 | $198,976 | 19 | <$5M | Research |
| Sussex Food Services, Inc. | Retail Trade | $192,600 | $193,787 | 48 | $16.1M | Research |
| Dawson & Bedsworth Electrical | Construction | $184,500 | $144,304 | 12 | <$5M | Research |