| Green Valley Terrace Snf LLC | Health Care and Social Assistance | $1,320,070 | $1,341,589 | 326 | $55.5M |  Research |
| Tortella Enterprises Inc. | Accommodation and Food Services | $1,265,740 | $1,278,016 | 223 | $39.6M | Research |
| Millsboro Auto Mart II LLC | Retail Trade | $802,000 | $811,245 | 49 | $12.3M | Research |
| Blue Hen Buzzards Dispose-All INC | Administrative and Support and Waste Management | $779,785 | $784,400 | 50 | $9.5M | Research |
| R S C Landscaping Limited | Administrative and Support and Waste Management | $769,000 | $774,255 | 147 | $31.8M | Research |
| Short's Marine INC | Retail Trade | $743,297 | $747,024 | 64 | $16.7M | Research |
| Short's Marine, INC | Retail Trade | $700,000 | $703,836 | 60 | $15.7M | Research |
| Caswell Holdings Co INC | Construction | $671,060 | $677,477 | 84 | $26.6M | Research |
| First Class Heating & Air Conditioning INC | Manufacturing | $532,800 | $536,100 | 48 | $12.6M | Research |
| Mid-Atlantic Electical Services | Manufacturing | $450,000 | $453,025 | 30 | $7.9M | Research |
| Baywood De LLC | Accommodation and Food Services | $406,547 | $408,418 | 86 | $15.3M | Research |
| Alpha Care Medical, LLC | Health Care and Social Assistance | $339,130 | $342,874 | 21 | $6.6M | Research |
| Denney Electric Supply of Delaware | Wholesale Trade | $334,375 | $336,581 | 26 | $8.0M | Research |
| Tortella Enterprises, INC | Accommodation and Food Services | $309,012 | $312,348 | 9 | <$5M | Research |
| Rickards Restoration INC | Other Services (except Public Administration) | $307,125 | $308,848 | 24 | <$5M | Research |
| Rickards Restorations & Auto Body INC | Other Services (except Public Administration) | $301,469 | $303,336 | 23 | <$5M | Research |
| Peninsula Dental, Llc. | Health Care and Social Assistance | $298,486 | $300,768 | 21 | <$5M | Research |
| Peninsula Dental Llc. | Health Care and Social Assistance | $289,310 | $292,584 | 21 | <$5M | Research |
| Tailbangers, Inc. | Manufacturing | $275,776 | $280,303 | 59 | $20.8M | Research |
| Dutton Bus Service | Transportation and Warehousing | $270,835 | $273,641 | 67 | $25.8M | Research |
| Dutton Bus Service, Inc. | Transportation and Warehousing | $265,750 | $268,238 | 73 | $28.1M | Research |
| Lewes Surgical and Medical Associates PA | Health Care and Social Assistance | $250,782 | $252,397 | 38 | $11.9M | Research |
| Blue Bag Ventures LLC | Accommodation and Food Services | $243,548 | $0 | 70 | $12.4M | Research |
| Baker's Hardware Co INC | Wholesale Trade | $231,898 | $233,149 | 30 | $9.2M | Research |
| Ellis Farms INC | Agriculture, Forestry, Fishing and Hunting | $225,472 | $179,631 | 20 | <$5M | Research |