| Conchy Joe's Restaurants Inc. | Accommodation and Food Services | $1,468,656 | $1,475,858 | 180 | $32.0M |  Research |
| Treasure Coast Medical Associates, Inc. | Health Care and Social Assistance | $1,282,500 | $671,126 | 64 | $20.1M | Research |
| Kg Restaurants LLC | Accommodation and Food Services | $1,152,389 | $1,168,490 | 124 | $22.0M | Research |
| Jensen Beach LLC | Accommodation and Food Services | $1,066,200 | $1,072,743 | 140 | $43.8M | Research |
| Conchy Joe's Restaurants INC | Accommodation and Food Services | $1,049,000 | $1,057,679 | 187 | $33.2M | Research |
| Hibiscus Childrens Center INC | Health Care and Social Assistance | $977,000 | $987,546 | 148 | N/A | Research |
| Kg Restaurants LLC | Accommodation and Food Services | $877,000 | $888,815 | 135 | $24.0M | Research |
| Just Believe Recovery Center of Carbondale LLC | Health Care and Social Assistance | $820,900 | $828,425 | 96 | $19.0M | Research |
| Hps, Helping People Succeed Inc. | Other Services (except Public Administration) | $810,700 | $817,785 | 55 | N/A | Research |
| Just Believe Recovery Center of Carbondale | Health Care and Social Assistance | $649,495 | $652,093 | 40 | $6.8M | Research |
| Jbrc Medical LLC | Health Care and Social Assistance | $630,825 | $643,476 | 43 | $7.3M | Research |
| Jbrc Medical LLC | Health Care and Social Assistance | $624,498 | $629,306 | 43 | $7.3M | Research |
| One Hc-Jensen Beach LLC | Health Care and Social Assistance | $549,619 | $555,266 | 92 | $15.7M | Research |
| Stuart Paint & Supply INC | Retail Trade | $511,200 | $514,494 | 54 | $11.1M | Research |
| Cash-2-U Financial Services of Virginia LLC | Finance and Insurance | $416,900 | $0 | 54 | $27.7M | Research |
| Cast Finance LLC | Real Estate and Rental and Leasing | $408,200 | $307,186 | 22 | <$5M | Research |
| Total Lifesafety Corp | Administrative and Support and Waste Management | $393,840 | $396,630 | 42 | $6.2M | Research |
| R & M Fabrics INC | Retail Trade | $386,049 | $398,736 | 54 | $12.7M | Research |
| DBA Rick Carroll Insurance Agency | Finance and Insurance | $381,195 | $288,261 | 28 | $14.4M | Research |
| The Transit Group, INC | Professional, Scientific, and Technical Services | $372,600 | $387,244 | 53 | $5.5M | Research |
| Premier Physical Therapy and Sports Medicine INC | Health Care and Social Assistance | $369,625 | $372,795 | 40 | $10.8M | Research |
| Just Believe Recovery Center of Port Saint Lucie LLC | Health Care and Social Assistance | $299,417 | $301,706 | 34 | $5.8M | Research |
| All Partners Network Pllc | Health Care and Social Assistance | $288,440 | $290,700 | 34 | $8.0M | Research |
| Kopp Development Inc. | Manufacturing | $280,182 | $283,583 | 19 | <$5M | Research |
| Wholesale Marine Specialists INC | Other Services (except Public Administration) | $262,400 | $204,570 | 23 | <$5M | Research |