| West Florida Medical Center Clinic, PA | Health Care and Social Assistance | $5,862,600 | $5,933,114 | 485 | $152.2M |  Research |
| Escambia Community Clinics, INC | Health Care and Social Assistance | $4,324,100 | $4,384,758 | 341 | N/A | Research |
| Sandy Sansing Cars, INC | Retail Trade | $4,245,800 | $4,295,452 | 352 | $88.7M | Research |
| The Lewis Bear Company | Wholesale Trade | $2,956,700 | $2,989,750 | 260 | $66.9M | Research |
| Woodlands Medical Specialists, P.a. | Health Care and Social Assistance | $2,773,480 | $2,809,535 | 270 | $63.2M | Research |
| Saltmarsh Cleaveland & Gund PA | Professional, Scientific, and Technical Services | $2,443,200 | $2,471,229 | 140 | $44.6M | Research |
| Panhandle Anesthesiology Associates, PA | Health Care and Social Assistance | $2,408,400 | $2,436,699 | 97 | $30.4M | Research |
| Levin Papantonio Thomas Mitchell Rafferty & Proctor PA | Professional, Scientific, and Technical Services | $2,400,000 | $2,426,733 | 315 | $76.5M | Research |
| Bayside Structures LLC | Mining, Quarrying, and Oil and Gas Extraction | $2,316,035 | $2,351,676 | 254 | $15.4M | Research |
| Radiology Associates of Pensacola PA | Health Care and Social Assistance | $2,300,000 | $372,800 | 18 | $5.6M | Research |
| Cbak, Inc. | Accommodation and Food Services | $2,149,025 | $2,174,107 | 317 | $56.3M | Research |
| Southern Erectors INC | Manufacturing | $2,000,000 | $1,848,566 | 212 | $55.5M | Research |
| Bayside Structures LLC | Construction | $2,000,000 | $2,010,444 | 174 | $198.2M | Research |
| Flora-Bama Management LLC | Accommodation and Food Services | $2,000,000 | $2,014,222 | 287 | $35.2M | Research |
| Aylstock Witkin Kreis & Overholtz Pllc | Professional, Scientific, and Technical Services | $1,988,733 | $2,012,432 | 223 | $54.2M | Research |
| Aylstock, Witkin, Kreis & Overholtz, Plc | Professional, Scientific, and Technical Services | $1,988,700 | $2,012,564 | 209 | $50.8M | Research |
| Pensacola Motor Sales Inc. | Retail Trade | $1,957,743 | $1,975,852 | 180 | $45.4M | Research |
| Flora Bama Management LLC | Retail Trade | $1,950,400 | $1,972,396 | 407 | $62.2M | Research |
| Covenant Home Health Care, LLC | Health Care and Social Assistance | $1,894,200 | $1,921,508 | 150 | $24.3M | Research |
| Free Beer Tomorrow | Accommodation and Food Services | $1,877,900 | $1,813,007 | 268 | $47.6M | Research |
| Solaris Healthcare Pensacola, LLC | Health Care and Social Assistance | $1,811,612 | $1,832,496 | 213 | $36.2M | Research |
| Rehabilitation Center at Park Place LLC | Health Care and Social Assistance | $1,765,000 | $1,774,478 | 132 | $22.5M | Research |
| Pete Moore Chevrolet, Inc. | Retail Trade | $1,703,517 | $1,714,590 | 146 | $36.8M | Research |
| Jupiter Bach North America INC | Manufacturing | $1,688,022 | $679,872 | 186 | $48.7M | Research |
| Jerry Pate Turf & Irrigation, Inc. | Retail Trade | $1,666,900 | $1,677,312 | 134 | $27.7M | Research |