| Tallahassee Orthopedic Clinic Iii, P.l. | Health Care and Social Assistance | $4,254,700 | $4,324,075 | 304 | $95.4M | Research |
| Tallahassee Primary Care Associates, P.a. | Health Care and Social Assistance | $3,603,500 | $3,649,704 | 318 | $99.8M | Research |
| Radiology Associates of Tallahassee, P.a. | Health Care and Social Assistance | $3,198,678 | $3,233,732 | 206 | $64.7M | Research |
| Rei Holding Company | Manufacturing | $3,105,000 | $3,139,845 | 240 | $62.8M | Research |
| Preferred Managing Agency LLC | Management of Companies and Enterprises | $2,869,432 | $2,753,302 | 192 | $31.6M | Research |
| Big Bend Hospice Foundation INC | Health Care and Social Assistance | $2,726,500 | $2,757,552 | 218 | N/A | Research |
| Dermatology Associates of Tallahassee PA | Health Care and Social Assistance | $2,689,900 | $2,721,506 | 255 | $80.0M | Research |
| Goodwill Industries Big Bend INC | Health Care and Social Assistance | $2,628,708 | $2,641,599 | 500 | $81.0M | Research |
| Twin Oaks Juvenile Development, Inc. | Health Care and Social Assistance | $2,464,967 | $2,497,012 | 389 | N/A | Research |
| Jv & Sons, INC | Accommodation and Food Services | $2,210,900 | $2,238,400 | 499 | $88.6M | Research |
| Nova Technologies an Employee-Owned Engineering Company | Professional, Scientific, and Technical Services | $2,172,715 | $0 | 260 | $32.1M | Research |
| Proctor Holding Co. INC | Retail Trade | $2,000,250 | $2,018,586 | 185 | $46.6M | Research |
| Timothy D. Padgett P.a. | Professional, Scientific, and Technical Services | $2,000,000 | $2,020,222 | 138 | $33.5M | Research |
| Municipal Code Corporation | Information | $1,987,500 | $2,006,436 | 168 | $28.2M | Research |
| Tadlock Roofing Inc. | Construction | $1,984,000 | $1,994,747 | 250 | $82.4M | Research |
| Proctor Holding Company INC | Retail Trade | $1,966,533 | $1,976,639 | 145 | $36.5M | Research |
| Tadlock Roofing INC | Construction | $1,882,800 | $1,899,065 | 140 | $46.2M | Research |
| Fbmc Benefits Management INC | Finance and Insurance | $1,860,736 | $1,870,066 | 122 | $62.7M | Research |
| Timothy D Padgett, PA | Professional, Scientific, and Technical Services | $1,818,300 | $1,834,160 | 164 | $39.9M | Research |
| Figg Group, Inc. | Construction | $1,810,200 | $1,830,633 | 76 | $23.6M | Research |
| Bobbin Trace Automotive LLC | Retail Trade | $1,797,008 | $1,806,116 | 156 | $39.3M | Research |
| Centre Pointe Hrc LLC | Health Care and Social Assistance | $1,789,200 | $1,814,497 | 294 | $50.0M | Research |
| Bobbin Trace Automotive, LLC | Retail Trade | $1,776,253 | $1,790,998 | 150 | $37.8M | Research |
| Lscu Service Corporation, Inc. | Finance and Insurance | $1,770,059 | $1,788,497 | 103 | $52.9M | Research |
| Southern Medical Group P. A. | Health Care and Social Assistance | $1,634,471 | $1,648,546 | 78 | $24.5M | Research |