| Visiting Nurse Association of the Treasure Coast, INC | Health Care and Social Assistance | $4,580,572 | $4,631,467 | 477 | N/A |  Research |
| Medical Data Systems INC | Wholesale Trade | $3,821,835 | $3,865,708 | 413 | $126.5M | Research |
| Hra Holdings, LLC | Finance and Insurance | $2,762,500 | $0 | 500 | $256.9M | Research |
| Treasure Coast Community Health, INC | Health Care and Social Assistance | $2,671,570 | $2,701,328 | 276 | $86.6M | Research |
| Boston Barricade Company, Inc. | Real Estate and Rental and Leasing | $2,438,000 | $2,017,858 | 200 | $90.4M | Research |
| Boston Barricade Company Inc. | Real Estate and Rental and Leasing | $2,000,000 | $2,012,778 | 111 | $50.2M | Research |
| Quail Valley Club, LLC | Arts, Entertainment, and Recreation | $1,683,352 | $1,694,808 | 237 | $33.2M | Research |
| Parabel USA INC | Agriculture, Forestry, Fishing and Hunting | $1,659,815 | $1,670,911 | 68 | $6.9M | Research |
| Parabel USA INC | Agriculture, Forestry, Fishing and Hunting | $1,659,810 | $1,677,318 | 65 | $6.6M | Research |
| Saint Edward's School | Educational Services | $1,528,000 | $1,358,744 | 135 | N/A | Research |
| White Glove Holdings of Vero LLC | Transportation and Warehousing | $1,500,000 | $458,957 | 51 | $19.8M | Research |
| Vero Hotel LLC | Accommodation and Food Services | $1,465,900 | $1,478,116 | 107 | $33.5M | Research |
| Energy Solution Services, LLC | Mining, Quarrying, and Oil and Gas Extraction | $1,436,727 | $0 | 17 | <$5M | Research |
| El Dorado Financial INC | Professional, Scientific, and Technical Services | $1,335,147 | $1,342,499 | 123 | $39.1M | Research |
| Indrio Brands, LLC | Retail Trade | $1,329,300 | $1,345,584 | 195 | $46.6M | Research |
| Communications International Inc. | Other Services (except Public Administration) | $1,328,900 | $1,797,815 | 130 | $25.5M | Research |
| S S and M Automotive INC | Retail Trade | $1,317,300 | $1,325,643 | 111 | $28.0M | Research |
| El Dorado Financial, Inc. | Finance and Insurance | $1,249,895 | $1,260,956 | 148 | $76.0M | Research |
| Bendcare LLC | Professional, Scientific, and Technical Services | $1,187,700 | $1,195,948 | 75 | $7.8M | Research |
| Vero Orthopaedics Ii, P.a. | Health Care and Social Assistance | $1,154,513 | $1,169,361 | 82 | $25.7M | Research |
| Primary Care of the Treasure Coast, Inc. | Health Care and Social Assistance | $1,153,663 | $1,161,533 | 103 | $32.3M | Research |
| Cabana Beach Hotel & Resort LLC | Accommodation and Food Services | $1,132,108 | $1,144,980 | 125 | $39.1M | Research |
| Vatland Imports, Inc. | Retail Trade | $1,087,140 | $1,093,655 | 102 | $25.7M | Research |
| Proctor Construction Company LLC | Construction | $1,082,700 | $787,722 | 52 | $59.2M | Research |
| Ocean Grill INC | Accommodation and Food Services | $1,068,385 | $1,073,341 | 158 | $28.1M | Research |