| Bayport Inn LLC | Accommodation and Food Services | $238,186 | $240,461 | 51 | $9.1M |  Research |
| Idicula Medical Associates MD PA | Health Care and Social Assistance | $235,303 | $237,333 | 24 | $7.5M | Research |
| Pure Possibilities, Inc. | Other Services (except Public Administration) | $228,492 | $231,121 | 45 | $8.6M | Research |
| USA Tree Service LLC | Agriculture, Forestry, Fishing and Hunting | $200,000 | $202,789 | 22 | <$5M | Research |
| Palmwood Construction, LLC | Construction | $168,954 | $170,722 | 20 | $6.1M | Research |
| Premier Pharmacy Labs INC | Wholesale Trade | $151,500 | $152,633 | 12 | <$5M | Research |
| Church in the Wildwood (christian) INC | Other Services (except Public Administration) | $137,893 | $138,395 | 26 | N/A | Research |
| Church in the Wildwood, Christian INC | Other Services (except Public Administration) | $133,630 | $134,802 | 26 | N/A | Research |
| Polly T Michaels Dmd PA | Health Care and Social Assistance | $128,947 | $129,654 | 12 | <$5M | Research |
| All Tech Water Systems LLC | Construction | $125,200 | $53,255 | 10 | <$5M | Research |
| Joseph Mazzuco Construction INC | Construction | $125,000 | $82,814 | 18 | $5.5M | Research |
| Clemente P Nunag MD PA | Health Care and Social Assistance | $120,803 | $122,017 | 9 | <$5M | Research |
| Crowncooperllc DBA Animal Care Center of Weeki Wachee | Professional, Scientific, and Technical Services | $111,988 | $112,985 | 13 | <$5M | Research |
| Affordable Dentures Weeki Wachee II PA | Unknown | $110,482 | $111,620 | 11 | N/A | Research |
| Melvin C Lu MD LLC | Health Care and Social Assistance | $109,912 | $111,225 | 14 | <$5M | Research |
| Palmwood Realty, INC | Real Estate and Rental and Leasing | $105,993 | $2,223 | 9 | <$5M | Research |
| Metro Mortuary Transport INC | Transportation and Warehousing | $89,918 | $90,815 | 12 | <$5M | Research |
| Elite Auto Detail INC | Other Services (except Public Administration) | $86,500 | $87,286 | 13 | <$5M | Research |
| Suncoast Mobile Welding, LLC | Other Services (except Public Administration) | $86,375 | $87,601 | 10 | <$5M | Research |
| Maya Motels Inc. | Accommodation and Food Services | $84,787 | $85,216 | 19 | $5.9M | Research |
| Martucci Concrete Pumping LLC | Construction | $84,549 | $85,200 | 11 | <$5M | Research |
| Joneleen LLC | Retail Trade | $83,191 | $83,464 | 10 | <$5M | Research |
| Cdp Enterprises INC | Accommodation and Food Services | $79,087 | $79,919 | 25 | <$5M | Research |
| West Coast Classic, INC | Other Services (except Public Administration) | $76,779 | $77,295 | 15 | <$5M | Research |
| Bmj Supply,inc | Wholesale Trade | $73,492 | $74,160 | 7 | <$5M | Research |