| Kennedy Network Services, Inc. | Construction | $484,700 | $489,035 | 48 | $18.0M |  Research |
| Kennedy Network Services INC | Information | $466,810 | $468,755 | 47 | $7.9M | Research |
| Mosley Family Poultry Farms INC | Wholesale Trade | $450,157 | $0 | 35 | $9.0M | Research |
| Environmental Wood Products, Inc. | Manufacturing | $175,500 | $176,486 | 21 | $20.8M | Research |
| Collins Mobile Home Sales, Inc. | Retail Trade | $135,759 | $137,022 | 21 | <$5M | Research |
| Hillside Gardens USA INC | Wholesale Trade | $131,900 | $133,164 | 24 | $6.2M | Research |
| Collins Mobile Homes INC | Retail Trade | $119,192 | $120,212 | 17 | <$5M | Research |
| Oso Sweet Farms LLC | Agriculture, Forestry, Fishing and Hunting | $113,500 | $114,815 | 10 | <$5M | Research |
| Tri-Care INC | Retail Trade | $101,100 | $101,707 | 33 | $5.8M | Research |
| Agritech Building Systems, Inc. | Construction | $90,000 | $90,710 | 10 | $11.4M | Research |
| Reidsville Veterinary Clinic, Inc. | Professional, Scientific, and Technical Services | $59,500 | $60,136 | 16 | <$5M | Research |
| Ornelas Harvesting, Inc. | Agriculture, Forestry, Fishing and Hunting | $59,100 | $59,696 | 6 | <$5M | Research |
| Kamela Inc. DBA Reidsville Dq | Accommodation and Food Services | $52,800 | $53,327 | 20 | <$5M | Research |
| Collins Holding Company INC | Real Estate and Rental and Leasing | $43,882 | $44,264 | 6 | <$5M | Research |
| Tootle Spreader Service, Inc. | Agriculture, Forestry, Fishing and Hunting | $42,300 | $42,618 | 6 | <$5M | Research |
| Reidsville Electric, INC | Retail Trade | $40,900 | $41,340 | 8 | <$5M | Research |
| The Tattnall Journal, INC | Information | $40,000 | $40,373 | 10 | <$5M | Research |
| Hodges Bros. Enterprises Inc. | Construction | $39,867 | $40,026 | 2 | <$5M | Research |
| D. Wilson, Inc. | Finance and Insurance | $34,200 | $34,421 | 7 | <$5M | Research |
| Collins Holding Company Inc. | Retail Trade | $33,454 | $33,775 | 6 | <$5M | Research |
| Gregorio Tlacuatl | Agriculture, Forestry, Fishing and Hunting | $30,300 | $30,606 | 2 | <$5M | Research |
| Bradley B Anderson Funeral Services INC | Other Services (except Public Administration) | $28,800 | $29,167 | 13 | <$5M | Research |
| Merrill Anderson Trucking, Inc. | Transportation and Warehousing | $28,400 | $28,591 | 3 | <$5M | Research |
| Ringer Veterinary Hospital, LLC | Professional, Scientific, and Technical Services | $26,973 | $27,147 | 7 | <$5M | Research |
| Jim Jordan Farm INC | Agriculture, Forestry, Fishing and Hunting | $26,500 | $26,826 | 6 | <$5M | Research |