| Illinois Bone and Joint Institute LLC | Health Care and Social Assistance | $10,000,000 | $10,110,411 | 500 | $156.9M |  Research |
| Lutheran Social Services of Illinois | Other Services (except Public Administration) | $9,985,367 | $10,101,586 | 500 | N/A | Research |
| Institute of Gas Technology | Professional, Scientific, and Technical Services | $8,548,767 | $8,353,937 | 410 | $85.2M | Research |
| Lorig Construction Company | Construction | $7,403,982 | $7,485,324 | 374 | $115.9M | Research |
| Svanaco, Inc. | Professional, Scientific, and Technical Services | $6,287,000 | $6,360,523 | 385 | $79.6M | Research |
| Jupiter Aluminum Corp. | Manufacturing | $5,799,700 | $5,868,820 | 424 | $111.0M | Research |
| Ims Companies, LLC | Manufacturing | $5,616,300 | $5,681,980 | 500 | $130.9M | Research |
| Warehouse Direct, Inc. | Wholesale Trade | $5,158,400 | $5,218,181 | 321 | $82.6M | Research |
| Mcshane Construction Company LLC | Construction | $3,765,765 | $3,817,963 | 38 | $43.3M | Research |
| W. Diamond Group Corporation | Manufacturing | $3,640,100 | $3,681,658 | 294 | $103.8M | Research |
| Finzer Roller Inc. | Manufacturing | $3,144,100 | $3,119,583 | 221 | $219.2M | Research |
| Nu-Way Industries, Inc. | Manufacturing | $3,100,000 | $3,137,200 | 226 | $55.2M | Research |
| Print Management Partners, Inc. | Manufacturing | $2,523,656 | $2,552,258 | 154 | $152.7M | Research |
| Gebruder Weiss INC | Transportation and Warehousing | $2,360,142 | $2,386,912 | 131 | $50.7M | Research |
| Cfc Inc. | Manufacturing | $2,271,000 | $2,297,558 | 126 | $44.5M | Research |
| Do and Co Chicago Catering, Inc. | Accommodation and Food Services | $2,235,500 | $2,142,607 | 259 | $48.3M | Research |
| United States Drug Testing Laboratories Inc. | Health Care and Social Assistance | $2,166,586 | $2,191,863 | 160 | $37.1M | Research |
| Magnum Insurance Agency Co., Inc. | Finance and Insurance | $2,092,000 | $2,120,543 | 236 | $103.8M | Research |
| Mac Rx, LLC | Wholesale Trade | $2,067,100 | $1,936,827 | 187 | $48.1M | Research |
| Do & Co Chicago Catering Inc. | Accommodation and Food Services | $2,000,000 | $0 | 281 | $52.5M | Research |
| Illinois Cafe & Service Co. | Accommodation and Food Services | $2,000,000 | $2,022,444 | 500 | $88.8M | Research |
| W Diamond Group Corporation | Manufacturing | $2,000,000 | $2,016,778 | 271 | $95.6M | Research |
| Seneca Nursing Home, INC | Health Care and Social Assistance | $1,995,242 | $2,011,751 | 231 | $39.3M | Research |
| American Louver Company | Manufacturing | $1,853,200 | $1,870,085 | 123 | $32.2M | Research |
| Anderson Lock Company Ltd. | Administrative and Support and Waste Management | $1,833,272 | $1,848,447 | 103 | $15.1M | Research |