| Hoyleton Youth and Family Services | Health Care and Social Assistance | $1,916,900 | $1,935,176 | 203 | N/A |  Research |
| Illinois Center for Autism | Health Care and Social Assistance | $1,023,400 | $1,030,325 | 102 | N/A | Research |
| Pyramid Electrical Contractors INC | Construction | $974,000 | $981,552 | 50 | $16.5M | Research |
| Lotawata Creek INC | Accommodation and Food Services | $865,679 | $876,837 | 70 | $12.4M | Research |
| Pass, L.l.c. | Administrative and Support and Waste Management | $729,245 | $776,456 | 49 | $7.2M | Research |
| The Hinrichs Group, Inc. | Construction | $630,985 | $634,526 | 38 | $43.3M | Research |
| The Hinrichs Group INC | Construction | $630,985 | $633,632 | 38 | $43.3M | Research |
| Lotawata Creek INC | Accommodation and Food Services | $618,342 | $624,474 | 136 | $24.1M | Research |
| Commercial Landscape Services Inc. | Administrative and Support and Waste Management | $469,223 | $471,399 | 28 | $6.1M | Research |
| Center for Gastrointestinal Health S.c. | Health Care and Social Assistance | $388,996 | $392,684 | 45 | $14.1M | Research |
| Commercial Landscape Services, Inc. | Administrative and Support and Waste Management | $375,438 | $377,513 | 28 | $6.1M | Research |
| Bcl Zapata INC | Accommodation and Food Services | $374,136 | $378,769 | 52 | $9.2M | Research |
| Center for Gastrointestinal Health Sc | Health Care and Social Assistance | $349,400 | $352,473 | 42 | $13.2M | Research |
| Internet Wines & Spirits Co | Retail Trade | $326,700 | $331,728 | 65 | $9.9M | Research |
| Eagle Publications, Inc. | Information | $325,700 | $235,305 | 21 | <$5M | Research |
| Jacob Family Enterprises INC | Construction | $321,000 | $324,504 | 26 | $9.7M | Research |
| Cloud 9 Hospitality LLC | Accommodation and Food Services | $308,500 | $311,302 | 44 | $13.8M | Research |
| Christ United Methodist Church of Fairview Heights | Other Services (except Public Administration) | $292,900 | $295,683 | 69 | N/A | Research |
| B.j. Diversified, Inc. | Other Services (except Public Administration) | $280,945 | $283,585 | 70 | $13.7M | Research |
| Holy Trinity Roman Catholic Church | Other Services (except Public Administration) | $268,987 | $270,409 | 59 | N/A | Research |
| Bcl Zapata INC | Accommodation and Food Services | $264,200 | $267,711 | 52 | $9.2M | Research |
| San Raphael INC - Saf0537 | Accommodation and Food Services | $261,969 | $264,732 | 8 | <$5M | Research |
| Lou Fusz Motor Company of Metro East | Retail Trade | $260,400 | $263,351 | 14 | <$5M | Research |
| Rich Rich & Cooksey PC | Professional, Scientific, and Technical Services | $258,700 | $261,790 | 17 | <$5M | Research |
| Gil Klein Tv & Appliance | Retail Trade | $257,500 | $258,883 | 30 | $9.2M | Research |