| Midwest Fire Consulting Group LLC | Administrative and Support and Waste Management | $49,325 | $49,610 | 10 | <$5M | AI Deep Dive |
| Reeves Smile Design | Health Care and Social Assistance | $48,500 | $49,120 | 7 | <$5M | AI Deep Dive |
| Rawson Excavating | Mining, Quarrying, and Oil and Gas Extraction | $47,000 | $47,294 | 3 | <$5M | AI Deep Dive |
| Mi Kulie LLC | Accommodation and Food Services | $46,564 | $46,783 | 13 | <$5M | AI Deep Dive |
| Cindy B's Cafe INC | Accommodation and Food Services | $46,564 | $46,763 | 13 | <$5M | AI Deep Dive |
| Stewarts Body Shop | Other Services (except Public Administration) | $45,544 | $46,031 | 5 | <$5M | AI Deep Dive |
| Cross and Flame Ministries | Other Services (except Public Administration) | $43,631 | $43,868 | 8 | N/A | AI Deep Dive |
| Aaron Savka | Manufacturing | $42,479 | $42,809 | 5 | <$5M | AI Deep Dive |
| Thread Fx | Manufacturing | $42,400 | $42,846 | 5 | <$5M | AI Deep Dive |
| Von Jakob Vineyard, Ltd | Manufacturing | $42,200 | $42,668 | 7 | <$5M | AI Deep Dive |
| First Baptist Church of Murphysboro | Other Services (except Public Administration) | $41,647 | $41,849 | 9 | N/A | AI Deep Dive |
| Flowers Truck Service Inc. | Transportation and Warehousing | $41,600 | $42,030 | 6 | <$5M | AI Deep Dive |
| Larry Worthen | Retail Trade | $41,476 | $41,596 | 4 | <$5M | AI Deep Dive |
| Howard Mileur | Agriculture, Forestry, Fishing and Hunting | $40,014 | $40,236 | 8 | <$5M | AI Deep Dive |
| Jackson County Abstract & Title Guarantee Co, INC | Real Estate and Rental and Leasing | $40,000 | $40,370 | 5 | <$5M | AI Deep Dive |
| First Baptist Church of Murphysboro | Other Services (except Public Administration) | $40,000 | $40,277 | 9 | N/A | AI Deep Dive |
| Murphysboro Chiropractic Clinic, P.c. | Health Care and Social Assistance | $40,000 | $33,917 | 8 | <$5M | AI Deep Dive |
| Bishop & Elwell Insurance Agency, Inc. | Finance and Insurance | $39,733 | $40,004 | 7 | <$5M | AI Deep Dive |
| Stan Graeff State Farm Insurance | Finance and Insurance | $38,779 | $39,048 | 2 | <$5M | AI Deep Dive |
| Gary a Tretter | Agriculture, Forestry, Fishing and Hunting | $38,411 | $38,519 | 5 | <$5M | AI Deep Dive |
| Local 160 Joint Apprenticeship Committee | Other Services (except Public Administration) | $37,854 | $37,989 | 7 | N/A | AI Deep Dive |
| Erle Tomlinson | Accommodation and Food Services | $37,854 | $38,028 | 12 | <$5M | AI Deep Dive |
| Humane Society of Southern Illinois/spca Inc. | Other Services (except Public Administration) | $36,400 | $36,775 | 14 | N/A | AI Deep Dive |
| Kimverly Kalaher | Health Care and Social Assistance | $35,706 | $35,959 | 3 | <$5M | AI Deep Dive |
| B Ozburn Insurance Agency Inc. | Finance and Insurance | $35,625 | $35,778 | 5 | <$5M | AI Deep Dive |