| Salem Township Hospital | Health Care and Social Assistance | $2,598,182 | $2,627,438 | 206 | N/A | AI Deep Dive |
| Marion County Horizon Center | Health Care and Social Assistance | $1,482,500 | $1,494,648 | 238 | N/A | AI Deep Dive |
| Bettendorf Stanford Holdings | Manufacturing | $1,417,400 | $1,434,253 | 125 | $32.7M | AI Deep Dive |
| Shivam Hotel LLC | Accommodation and Food Services | $897,124 | $901,941 | 105 | $32.8M | AI Deep Dive |
| Americana Outdoors INC | Manufacturing | $886,000 | $891,243 | 81 | $19.8M | AI Deep Dive |
| Atvs and More Inc. | Retail Trade | $620,463 | $628,164 | 53 | $13.8M | AI Deep Dive |
| Health Care Management Corporation | Health Care and Social Assistance | $568,000 | $572,465 | 104 | $17.7M | AI Deep Dive |
| United Medical Response LLC | Health Care and Social Assistance | $564,150 | $571,136 | 75 | $17.4M | AI Deep Dive |
| Cila Corporation | Health Care and Social Assistance | $496,000 | $498,922 | 74 | N/A | AI Deep Dive |
| Schmidt Ford of Salem Inc. | Retail Trade | $489,662 | $493,448 | 36 | $9.1M | AI Deep Dive |
| Schmidt Ford of Salem, INC | Retail Trade | $489,660 | $496,058 | 36 | $9.1M | AI Deep Dive |
| The Meador Boys Express, INC | Transportation and Warehousing | $412,100 | $415,239 | 28 | $6.4M | AI Deep Dive |
| The Meador Boys Express INC | Transportation and Warehousing | $381,418 | $383,153 | 27 | $10.5M | AI Deep Dive |
| Security Alarm Corporation | Administrative and Support and Waste Management | $375,000 | $377,229 | 30 | $5.7M | AI Deep Dive |
| Landers Automotive Corporation | Other Services (except Public Administration) | $352,700 | $355,296 | 38 | $7.4M | AI Deep Dive |
| Shakespeare Oil Company, Inc. | Mining, Quarrying, and Oil and Gas Extraction | $317,000 | $319,032 | 18 | <$5M | AI Deep Dive |
| Salem Tire Center, INC | Retail Trade | $316,100 | $319,174 | 42 | $11.4M | AI Deep Dive |
| Bandys Pharmacy, INC | Retail Trade | $231,200 | $232,923 | 21 | <$5M | AI Deep Dive |
| Shawnee Stone, LLC | Mining, Quarrying, and Oil and Gas Extraction | $223,300 | $224,664 | 18 | <$5M | AI Deep Dive |
| Precision Insurance & Financial Services, Inc. | Finance and Insurance | $218,100 | $219,516 | 21 | $10.8M | AI Deep Dive |
| Timtam, Inc. | Accommodation and Food Services | $212,760 | $215,016 | 61 | $10.8M | AI Deep Dive |
| Twin Willows Nursing Center INC | Health Care and Social Assistance | $211,800 | $214,836 | 32 | $5.4M | AI Deep Dive |
| Jones' Salem Foods, Inc. | Retail Trade | $209,900 | $211,037 | 59 | $14.7M | AI Deep Dive |
| Salem Energy Savers INC | Manufacturing | $206,500 | $207,994 | 16 | <$5M | AI Deep Dive |
| Salem Energy Savers INC | Manufacturing | $180,310 | $182,009 | 15 | <$5M | AI Deep Dive |