| Sioux Center Health | Health Care and Social Assistance | $4,388,200 | $4,436,651 | 354 | N/A |  Research |
| Dordt University | Educational Services | $4,000,000 | $4,051,616 | 353 | N/A | Research |
| Link Mfg. Ltd | Manufacturing | $2,736,900 | $2,768,618 | 178 | $46.6M | Research |
| Center Fresh Egg Farm LLP | Agriculture, Forestry, Fishing and Hunting | $2,086,321 | $2,012,365 | 140 | $22.9M | Research |
| Groschopp, INC | Manufacturing | $2,001,000 | $2,024,080 | 173 | $45.3M | Research |
| Hawkeye Pride Egg Farms LLP | Agriculture, Forestry, Fishing and Hunting | $1,469,120 | $1,374,286 | 98 | $16.0M | Research |
| Mutual Telephone Company of Sioux Center, Iowa | Information | $1,402,600 | $1,414,781 | 85 | $14.3M | Research |
| Sioux Automation Center, Inc. | Manufacturing | $1,288,500 | $1,296,902 | 152 | $39.8M | Research |
| Bar K Cattle LLC | Agriculture, Forestry, Fishing and Hunting | $1,033,305 | $1,040,948 | 155 | $25.4M | Research |
| Bar K Cattle LLC | Agriculture, Forestry, Fishing and Hunting | $924,500 | $930,296 | 104 | $17.0M | Research |
| Cooperative Gas & Oil Company | Retail Trade | $758,960 | $763,451 | 89 | $29.8M | Research |
| Plumbing & Heating Wholesale, | Wholesale Trade | $754,000 | $761,226 | 68 | $20.8M | Research |
| Cooperative Gas & Oil Company | Retail Trade | $719,500 | $725,926 | 58 | $13.9M | Research |
| Siouxland Energy Cooperative | Manufacturing | $691,290 | $695,192 | 43 | $42.6M | Research |
| Siouxland Energy Cooperative | Manufacturing | $691,200 | $696,919 | 45 | $44.6M | Research |
| Ambank Insurance Inc. | Finance and Insurance | $624,000 | $630,188 | 44 | $22.6M | Research |
| Greater Sioux Community Health Center Inc. | Health Care and Social Assistance | $589,525 | $592,755 | 54 | N/A | Research |
| Kroese & Kroese, P.c. | Professional, Scientific, and Technical Services | $577,800 | $583,642 | 38 | $12.1M | Research |
| Sioux Center Christian School | Educational Services | $574,400 | $577,623 | 63 | N/A | Research |
| Greater Sioux Community Health Center, Inc. | Health Care and Social Assistance | $497,800 | $502,192 | 49 | N/A | Research |
| Ver Hoef Automotive, Inc. | Retail Trade | $486,900 | $491,235 | 40 | $10.1M | Research |
| Mouw Motor Company, Inc. | Retail Trade | $374,200 | $377,501 | 38 | $9.6M | Research |
| Rent-All, Inc. | Real Estate and Rental and Leasing | $368,700 | $371,185 | 33 | $14.9M | Research |
| Hueing, Inc. | Accommodation and Food Services | $360,000 | $362,456 | 125 | $22.2M | Research |
| Fibercomm Lc | Information | $350,400 | $352,349 | 23 | <$5M | Research |