| Buena Vista Regional Medical Center | Health Care and Social Assistance | $5,894,190 | $5,235,949 | 412 | N/A |  Research |
| Meridian Manufacturing, INC | Manufacturing | $1,325,100 | $1,340,817 | 116 | $30.4M | Research |
| Methodist Manor Retirement Community | Health Care and Social Assistance | $1,143,000 | $1,157,995 | 200 | N/A | Research |
| Liberty Food Service, Inc. | Accommodation and Food Services | $1,138,700 | $1,146,228 | 211 | $39.4M | Research |
| Harvest International INC | Manufacturing | $636,312 | $638,504 | 74 | $19.4M | Research |
| Nutra Tech I INC | Professional, Scientific, and Technical Services | $564,900 | $568,745 | 44 | <$5M | Research |
| Merrill Manufacturing Company | Manufacturing | $548,310 | $552,381 | 48 | $11.7M | Research |
| Sports Rehab Holdings, LLC | Health Care and Social Assistance | $527,000 | $530,294 | 45 | $7.3M | Research |
| Harvest International Inc. | Manufacturing | $489,997 | $493,726 | 55 | $14.4M | Research |
| United Community Health Center, INC | Health Care and Social Assistance | $476,174 | $480,433 | 38 | N/A | Research |
| United Community Health Center | Health Care and Social Assistance | $476,174 | $478,912 | 39 | N/A | Research |
| St. Mary's Parish | Other Services (except Public Administration) | $461,300 | $464,130 | 118 | $22.5M | Research |
| Saint Mary Church | Other Services (except Public Administration) | $420,540 | $422,479 | 134 | $25.6M | Research |
| Edwards Storm Lake, INC | Retail Trade | $390,575 | $394,242 | 27 | $6.8M | Research |
| Mills Agency INC | Professional, Scientific, and Technical Services | $302,000 | $303,688 | 20 | $6.4M | Research |
| The Mills Agency Inc. | Professional, Scientific, and Technical Services | $294,700 | $296,501 | 20 | <$5M | Research |
| Rosene Pickhinke Peters & Co PC | Professional, Scientific, and Technical Services | $226,500 | $227,758 | 17 | $5.4M | Research |
| Liberty L.c. | Accommodation and Food Services | $221,500 | $223,592 | 13 | <$5M | Research |
| Bargloff & Company | Manufacturing | $216,916 | $218,380 | 15 | <$5M | Research |
| Prairie Fabrication, LLC | Manufacturing | $214,948 | $216,125 | 24 | $5.9M | Research |
| Stalcup Agricultural Service, INC | Agriculture, Forestry, Fishing and Hunting | $208,332 | $209,698 | 14 | <$5M | Research |
| Stalcup Agricultural Service Inc. | Agriculture, Forestry, Fishing and Hunting | $208,332 | $209,466 | 14 | <$5M | Research |
| Hamilton Law Firm P.c. | Professional, Scientific, and Technical Services | $202,000 | $202,965 | 17 | <$5M | Research |
| Hamilton Law Firm, P.c. | Professional, Scientific, and Technical Services | $201,500 | $203,263 | 18 | <$5M | Research |
| Vision Care Associates, PC | Health Care and Social Assistance | $200,000 | $201,173 | 22 | $5.2M | Research |