| Brandenburg Telephone Company | Information | $1,675,200 | $1,685,623 | 129 | $21.7M |  Research |
| Meade County Rural Electric Coop | Utilities | $1,456,523 | $1,465,262 | 68 | N/A | Research |
| Powers Paper Company, Inc. | Manufacturing | $838,306 | $842,987 | 64 | $63.5M | Research |
| Tony Brown Chevrolet, Inc. | Retail Trade | $482,596 | $488,065 | 46 | $11.6M | Research |
| Neel Restaurants LLC | Accommodation and Food Services | $403,900 | $405,673 | 61 | $10.8M | Research |
| Jackson Hewitt Tax Service | Professional, Scientific, and Technical Services | $368,485 | $370,757 | 195 | $62.1M | Research |
| James Michael Jones | Professional, Scientific, and Technical Services | $368,485 | $369,877 | 156 | $49.7M | Research |
| Doe Valley Association, Inc. | Other Services (except Public Administration) | $259,713 | $261,120 | 32 | $6.1M | Research |
| Cool Beauty Consulting, Inc. | Retail Trade | $242,855 | $244,630 | 22 | <$5M | Research |
| Cool Beauty Consulting Inc. | Wholesale Trade | $223,568 | $224,264 | 19 | <$5M | Research |
| Meade Physicians Inc. | Health Care and Social Assistance | $193,700 | $202,596 | 24 | $7.5M | Research |
| Meade Physicians, Inc. | Health Care and Social Assistance | $193,700 | $194,738 | 24 | $7.5M | Research |
| Ray's Ford INC | Retail Trade | $180,700 | $181,844 | 24 | $6.0M | Research |
| Pharmboy Investments, LLC | Retail Trade | $174,165 | $175,514 | 18 | <$5M | Research |
| Outdoor Specialities Lawn & Landscaping LLC | Administrative and Support and Waste Management | $159,738 | $160,616 | 15 | <$5M | Research |
| K & G Variety, Inc. | Retail Trade | $144,900 | $146,281 | 22 | $5.2M | Research |
| Fashion Floors INC | Construction | $137,749 | $138,503 | 15 | <$5M | Research |
| Fashion Floors INC | Retail Trade | $137,749 | $138,274 | 10 | <$5M | Research |
| Robert Kupper | Health Care and Social Assistance | $109,800 | $83,591 | 9 | <$5M | Research |
| Home Plate Family Resturant LLC | Accommodation and Food Services | $103,597 | $104,102 | 17 | <$5M | Research |
| H and H Marketing # 1 | Retail Trade | $94,678 | $95,658 | 40 | $10.8M | Research |
| El Cid LLC | Accommodation and Food Services | $92,424 | $92,852 | 21 | <$5M | Research |
| Brandenburg Auto Clinic, LLP | Other Services (except Public Administration) | $92,300 | $93,164 | 15 | <$5M | Research |
| Wilson Pizza Ck Inc. | Accommodation and Food Services | $87,475 | $87,028 | 24 | <$5M | Research |
| Complete Family Care Practitioners, Pllc | Health Care and Social Assistance | $84,900 | $85,322 | 10 | <$5M | Research |