| The Federal Materials Company, LLC | Manufacturing | $505,565 | $509,540 | 47 | $46.6M |  AI Deep Dive |
| Marcum Engineering, LLC | Professional, Scientific, and Technical Services | $494,000 | $500,307 | 29 | <$5M | AI Deep Dive |
| James Transportation LLC | Transportation and Warehousing | $492,770 | $494,984 | 29 | $7.4M | AI Deep Dive |
| First-Line Fire Extinguisher Company | Wholesale Trade | $489,138 | $494,485 | 43 | $13.2M | AI Deep Dive |
| First-Line Fire Extinguisher Company | Public Administration | $489,000 | $494,439 | 46 | N/A | AI Deep Dive |
| Paducah Supply Company | Wholesale Trade | $476,400 | $481,204 | 33 | $10.1M | AI Deep Dive |
| Systems Solutions of Paducah, Inc. | Professional, Scientific, and Technical Services | $470,000 | $473,902 | 32 | $6.6M | AI Deep Dive |
| Acee's. Inc. | Retail Trade | $464,500 | $467,109 | 90 | $22.5M | AI Deep Dive |
| Ambulatory Surgery Center LLC | Health Care and Social Assistance | $460,590 | $465,878 | 204 | $36.3M | AI Deep Dive |
| Mad Payroll, LLC | Retail Trade | $457,900 | $462,818 | 54 | $9.4M | AI Deep Dive |
| Whitaker Marine Group LLC | Transportation and Warehousing | $447,900 | $450,023 | 29 | $7.4M | AI Deep Dive |
| Williams, Williams, & Lentz LLP | Professional, Scientific, and Technical Services | $434,485 | $436,935 | 22 | $7.0M | AI Deep Dive |
| St. Mary Catholic School System of Paducah, Inc. | Educational Services | $433,607 | $436,577 | 36 | N/A | AI Deep Dive |
| Hardway Enterprises LLC | Accommodation and Food Services | $432,982 | $436,518 | 57 | $10.1M | AI Deep Dive |
| Ambulatory Surgery Center, LLC | Health Care and Social Assistance | $432,747 | $438,308 | 43 | $7.7M | AI Deep Dive |
| Paducah Center for Health and Rehabilitation LLC | Health Care and Social Assistance | $427,251 | $0 | 68 | $11.6M | AI Deep Dive |
| Systems Solutions of Paducah Inc. | Retail Trade | $419,589 | $421,923 | 33 | $10.1M | AI Deep Dive |
| Chata Corp | Accommodation and Food Services | $407,011 | $409,532 | 105 | $18.6M | AI Deep Dive |
| Coad Autosales Inc. | Retail Trade | $396,900 | $400,241 | 40 | $10.1M | AI Deep Dive |
| Schroeder Publishing Company INC | Information | $382,970 | $384,817 | 21 | <$5M | AI Deep Dive |
| Schroeder Publishing Company, Inc. | Information | $382,900 | $385,397 | 37 | $6.2M | AI Deep Dive |
| Edwards Enterprises, LLC | Transportation and Warehousing | $382,200 | $387,121 | 20 | <$5M | AI Deep Dive |
| Edwards Enterprises LLC | Transportation and Warehousing | $381,277 | $385,623 | 20 | <$5M | AI Deep Dive |
| Royal Oaks Chevrolet Cadillac INC | Retail Trade | $378,678 | $382,423 | 43 | $10.8M | AI Deep Dive |
| Country Club of Paducah Inc. | Arts, Entertainment, and Recreation | $373,137 | $374,940 | 59 | N/A | AI Deep Dive |