| Acadian Contractors INC | Manufacturing | $6,442,703 | $6,512,955 | 406 | $99.2M |  Research |
| Abbeville General Hospital, INC | Health Care and Social Assistance | $5,197,200 | $4,890,392 | 478 | $94.8M | Research |
| Broussard Brothers, Inc. | Mining, Quarrying, and Oil and Gas Extraction | $3,347,753 | $3,385,908 | 188 | $11.4M | Research |
| Ecoserv, LLC | Mining, Quarrying, and Oil and Gas Extraction | $3,186,212 | $3,222,988 | 161 | $9.8M | Research |
| Seville Industries, LLC | Mining, Quarrying, and Oil and Gas Extraction | $2,578,351 | $700,901 | 53 | <$5M | Research |
| Ecoserv LLC | Mining, Quarrying, and Oil and Gas Extraction | $2,000,000 | $2,014,319 | 123 | $7.5M | Research |
| Seville Industries, LLC | Mining, Quarrying, and Oil and Gas Extraction | $1,590,000 | $0 | 53 | <$5M | Research |
| Gulf Coast Marine Fabricators INC | Mining, Quarrying, and Oil and Gas Extraction | $844,489 | $856,636 | 64 | <$5M | Research |
| Gulf Coast Companies, INC | Wholesale Trade | $798,522 | $806,217 | 56 | $14.4M | Research |
| Ray Chevrolet Olds, Inc. | Retail Trade | $746,700 | $754,412 | 96 | $24.2M | Research |
| Diversified Healthcare-Abbeville LLC | Health Care and Social Assistance | $739,800 | $749,417 | 139 | $23.6M | Research |
| Gulf Coast Marine Fabricators INC | Mining, Quarrying, and Oil and Gas Extraction | $652,000 | $579,951 | 53 | <$5M | Research |
| Transvac LLC | Transportation and Warehousing | $613,500 | $617,164 | 40 | $10.7M | Research |
| Transvac, LLC | Transportation and Warehousing | $613,500 | $617,488 | 61 | $13.9M | Research |
| N. R. Broussard Landing, Inc. | Transportation and Warehousing | $578,494 | $582,963 | 34 | <$5M | Research |
| Vision Production Chemicals LLC | Manufacturing | $516,100 | $519,833 | 30 | $29.8M | Research |
| Vision Production Chemica | Wholesale Trade | $511,166 | $515,423 | 23 | $5.9M | Research |
| T&m Aviation Inc. | Agriculture, Forestry, Fishing and Hunting | $411,534 | $413,982 | 26 | <$5M | Research |
| Smoke N Go LLC | Retail Trade | $385,500 | $388,922 | 49 | $7.6M | Research |
| Acadiana Shell & Limestone INC | Wholesale Trade | $378,300 | $380,124 | 46 | $14.1M | Research |
| Valour, L.l.c. | Administrative and Support and Waste Management | $377,320 | $380,823 | 22 | <$5M | Research |
| Pam Miller, INC | Accommodation and Food Services | $341,740 | $344,511 | 194 | $34.4M | Research |
| Vermilion Catholic High School | Other Services (except Public Administration) | $313,345 | $317,070 | 37 | N/A | Research |
| Deep South Financial Services, INC | Finance and Insurance | $308,731 | $0 | 33 | $17.0M | Research |
| Eagle Pest Control & Chemical INC | Administrative and Support and Waste Management | $266,600 | $268,046 | 27 | $5.8M | Research |