| Kinetix Broadband, LLC | Information | $442,200 | $444,632 | 39 | $6.5M |  Research |
| Hixson Brothers, LLC | Other Services (except Public Administration) | $434,000 | $436,700 | 45 | $8.6M | Research |
| Cecil D. Gassiott, LLC | Construction | $433,200 | $438,197 | 36 | $11.2M | Research |
| Louisiana Cardiovascular & Thoracic Institute, LLC | Health Care and Social Assistance | $432,250 | $436,200 | 24 | $7.5M | Research |
| Louisiana Cardiovascular & Thoracic Institute LLC | Health Care and Social Assistance | $432,250 | $435,024 | 20 | $6.3M | Research |
| Pes - Chicot INC DBA Lake Village Rehab | Health Care and Social Assistance | $430,917 | $435,023 | 96 | N/A | Research |
| J. Duncan Enterprises LLC | Accommodation and Food Services | $430,070 | $434,012 | 110 | $19.5M | Research |
| Walker Management Company of Alexandria, LLC | Retail Trade | $429,000 | $434,517 | 31 | $7.8M | Research |
| Tristate Health Services of Cenla LLC | Health Care and Social Assistance | $410,400 | $415,758 | 87 | $14.8M | Research |
| Cenla Heart Specialists, LLC | Health Care and Social Assistance | $409,600 | $413,275 | 37 | $11.6M | Research |
| First Pentecostal Church of Alexandria, Louisana, INC | Other Services (except Public Administration) | $406,300 | $411,604 | 24 | N/A | Research |
| Alexandria Country Day School | Educational Services | $405,600 | $407,966 | 45 | N/A | Research |
| Cecil D.. Gassiott LLC | Construction | $401,725 | $404,113 | 24 | $7.4M | Research |
| Southern Textile Services LLC | Other Services (except Public Administration) | $399,900 | $402,255 | 82 | $15.7M | Research |
| Freedman Clinic of Internal Medicine, LLP | Health Care and Social Assistance | $398,400 | $400,824 | 37 | $11.6M | Research |
| Freedman Memorial Cardiology | Health Care and Social Assistance | $398,200 | $400,445 | 40 | $7.9M | Research |
| The Arc Rapides Inc. | Educational Services | $391,750 | $394,264 | 80 | N/A | Research |
| The Arc Rapides, Inc. | Educational Services | $391,700 | $393,887 | 87 | N/A | Research |
| Mid Louisiana Surgical Specialists, Apmc | Health Care and Social Assistance | $391,200 | $393,330 | 27 | $8.5M | Research |
| Alexandria Neurosurgical Clinic | Health Care and Social Assistance | $384,200 | $386,495 | 28 | $8.8M | Research |
| Serenity Homecare, LLC | Health Care and Social Assistance | $380,295 | $385,327 | 40 | $6.9M | Research |
| Progressive Eldercare Services | Health Care and Social Assistance | $377,400 | $380,503 | 70 | N/A | Research |
| Walker Coa, LLC | Retail Trade | $370,700 | $375,499 | 37 | $9.3M | Research |
| Despino's Tire Service, INC | Retail Trade | $367,800 | $370,783 | 38 | $10.3M | Research |
| Ross Bus and Equipment Sales LLC | Transportation and Warehousing | $367,200 | $369,974 | 25 | $9.6M | Research |