| Standard Crane & Hoist, L.l.c. | Manufacturing | $1,163,703 | $1,175,709 | 83 | $21.7M |  Research |
| Cospolich, Inc. | Manufacturing | $904,100 | $917,636 | 89 | $23.3M | Research |
| Cospolich INC | Manufacturing | $834,715 | $841,903 | 72 | $18.9M | Research |
| Roman Catholic Congregation of St. Charles | Other Services (except Public Administration) | $460,000 | $465,281 | 67 | N/A | Research |
| Southern Chem Industries LLC | Manufacturing | $319,600 | $322,512 | 21 | $20.8M | Research |
| Unite Contracting LLC | Construction | $287,200 | $290,552 | 38 | $11.5M | Research |
| Unite Contracting LLC | Administrative and Support and Waste Management | $287,143 | $290,439 | 38 | $6.0M | Research |
| All Time Staffing INC | Administrative and Support and Waste Management | $206,332 | $208,974 | 23 | <$5M | Research |
| Zeringue's Plumbing & Mechanical INC | Construction | $205,377 | $206,980 | 15 | <$5M | Research |
| Riverbend Maintenance Corp | Other Services (except Public Administration) | $198,310 | $0 | 162 | $34.8M | Research |
| General Maritime Transportation Services Inc. | Transportation and Warehousing | $195,537 | $196,776 | 11 | <$5M | Research |
| General Maritime Transportation Services, Inc. | Transportation and Warehousing | $183,725 | $185,236 | 12 | <$5M | Research |
| Standard Industrial Services LLC | Other Services (except Public Administration) | $183,637 | $184,747 | 14 | <$5M | Research |
| Jesohn INC | Accommodation and Food Services | $181,815 | $184,136 | 50 | $8.9M | Research |
| Sport's Pub & Grill Inc. | Accommodation and Food Services | $154,738 | $156,263 | 19 | <$5M | Research |
| Jay Trusheim DBA None | Unknown | $142,057 | $143,825 | 9 | N/A | Research |
| Destrahan Animal Hosptial, Inc. | Professional, Scientific, and Technical Services | $141,900 | $143,248 | 17 | <$5M | Research |
| Hegwood and Company LLC | Professional, Scientific, and Technical Services | $136,100 | $136,986 | 9 | <$5M | Research |
| National Barge Service | Transportation and Warehousing | $129,106 | $130,143 | 12 | <$5M | Research |
| Sport's Pub & Grill Inc. | Accommodation and Food Services | $126,000 | $127,578 | 18 | <$5M | Research |
| River Road Market, LLC | Accommodation and Food Services | $124,260 | $124,930 | 46 | $8.2M | Research |
| Allison M. Hamada, D.d.s., L.l.c. | Unknown | $101,250 | $101,856 | 12 | N/A | Research |
| Destrehan Racquet and Golf, Inc. | Arts, Entertainment, and Recreation | $91,000 | $91,995 | 30 | N/A | Research |
| Destrehan Racquet and Golf INC | Arts, Entertainment, and Recreation | $89,625 | $90,398 | 22 | N/A | Research |
| River Road Historical Society | Arts, Entertainment, and Recreation | $88,215 | $88,607 | 34 | $5.2M | Research |