| Sai Gulf LLC | Professional, Scientific, and Technical Services | $1,000,000 | $1,012,056 | 95 | $13.3M |  Research |
| Angels Care LLC | Health Care and Social Assistance | $600,000 | $486,732 | 100 | $18.2M | Research |
| St. Charles Catholic High School | Educational Services | $534,273 | $537,420 | 45 | N/A | Research |
| Regal Industrial Group, LLC | Construction | $445,740 | $450,693 | 48 | $54.7M | Research |
| Neuromuscular Medical Associates LLC | Health Care and Social Assistance | $148,560 | $149,919 | 12 | <$5M | Research |
| Robert David Ory Jr & Benjamin Montegut Ory LLC | Health Care and Social Assistance | $139,415 | $141,200 | 9 | <$5M | Research |
| Performance Rehabilitation Services LLC | Health Care and Social Assistance | $133,100 | $134,912 | 8 | <$5M | Research |
| Robert David Ory Jr and Benjamin Montegut Ory LLC II | Health Care and Social Assistance | $112,417 | $113,447 | 8 | <$5M | Research |
| Riverside Urgent Care LLC | Health Care and Social Assistance | $107,700 | $108,185 | 16 | <$5M | Research |
| Pier 51 Seafood Restaurant & Oysterbar, INC | Accommodation and Food Services | $99,787 | $100,548 | 20 | <$5M | Research |
| Coastal Private Protection Security INC | Administrative and Support and Waste Management | $95,000 | $95,654 | 6 | <$5M | Research |
| Tatje Insurance & Financial Products, INC | Finance and Insurance | $86,155 | $87,244 | 7 | <$5M | Research |
| Premier Medical Rehab Laplace, INC | Health Care and Social Assistance | $85,700 | $86,285 | 5 | <$5M | Research |
| Riverlands Terminix INC | Administrative and Support and Waste Management | $85,020 | $86,102 | 7 | <$5M | Research |
| The Donut Hole LLC | Retail Trade | $76,600 | $77,408 | 10 | <$5M | Research |
| Laplace Wireless Communication INC | Information | $74,900 | $75,703 | 66 | $11.1M | Research |
| Garden of Eden Christian Academy, LLC | Health Care and Social Assistance | $69,762 | $70,541 | 27 | <$5M | Research |
| Rotolo's Destrehan LLC | Accommodation and Food Services | $69,100 | $69,728 | 14 | <$5M | Research |
| Ronald S. Aslett and Philip J. Kurica, LLP | Health Care and Social Assistance | $62,000 | $135,458 | 15 | <$5M | Research |
| William D. O'regan Iii, a Professional Law Corporation | Professional, Scientific, and Technical Services | $53,700 | $49,651 | 2 | <$5M | Research |
| Bec's at the Lake Restaurant & Catering, LLC | Accommodation and Food Services | $49,616 | $0 | 15 | <$5M | Research |
| Rotolo's Reserve LLC | Accommodation and Food Services | $48,311 | $48,745 | 14 | <$5M | Research |
| Wayne Jacobs Smoke House LLC | Accommodation and Food Services | $47,400 | $47,922 | 12 | <$5M | Research |
| Reve INC | Construction | $47,000 | $47,340 | 5 | <$5M | Research |
| Ml Production LLC | Arts, Entertainment, and Recreation | $46,250 | $0 | 3 | <$5M | Research |