| Opelousas Orthopaedic Clinic INC | Health Care and Social Assistance | $326,521 | $329,169 | 24 | $7.5M | AI Deep Dive |
| Roy Motors, Inc. | Other Services (except Public Administration) | $326,500 | $328,967 | 32 | $6.3M | AI Deep Dive |
| John S Dowling and Company | Professional, Scientific, and Technical Services | $289,000 | $291,192 | 21 | $6.7M | AI Deep Dive |
| Quality Care Providers of Louisiana, LLC | Health Care and Social Assistance | $286,000 | $287,617 | 97 | $16.6M | AI Deep Dive |
| Aspen Clinic, Inc. | Health Care and Social Assistance | $238,800 | $241,944 | 48 | $8.8M | AI Deep Dive |
| Cajun Chemicals and Janitorial Supply INC | Wholesale Trade | $237,680 | $239,766 | 22 | $5.7M | AI Deep Dive |
| Triad Energy Services, LLC | Transportation and Warehousing | $233,200 | $235,097 | 15 | <$5M | AI Deep Dive |
| Morrow Morrow Ryan & Bassett | Professional, Scientific, and Technical Services | $231,775 | $232,947 | 17 | <$5M | AI Deep Dive |
| Going Sebastien Fisher and Lebouef LLP | Professional, Scientific, and Technical Services | $225,689 | $228,811 | 12 | <$5M | AI Deep Dive |
| Piggly Wiggly South of Opelousas | Retail Trade | $225,651 | $227,676 | 111 | $27.7M | AI Deep Dive |
| Family Clinic Inc. | Health Care and Social Assistance | $222,572 | $224,019 | 27 | $8.5M | AI Deep Dive |
| Acadiana Medicine Clinic | Health Care and Social Assistance | $217,637 | $220,339 | 21 | <$5M | AI Deep Dive |
| Acadiana Medicine Clinic | Health Care and Social Assistance | $217,637 | $219,776 | 20 | $6.3M | AI Deep Dive |
| Jim Tatman's Mobile Homes INC | Retail Trade | $216,600 | $217,870 | 12 | <$5M | AI Deep Dive |
| Checkerboard Restaurants II INC | Accommodation and Food Services | $216,135 | $218,154 | 50 | $8.9M | AI Deep Dive |
| Ardoin & Kennedy LLC | Health Care and Social Assistance | $213,820 | $215,822 | 14 | <$5M | AI Deep Dive |
| Opelousas Family Worship Center Inc. | Educational Services | $209,100 | $210,624 | 31 | <$5M | AI Deep Dive |
| Dale's Food Store, INC | Retail Trade | $207,400 | $209,255 | 75 | $18.7M | AI Deep Dive |
| Morrow Morrow Ryan & Bassett | Professional, Scientific, and Technical Services | $206,245 | $228,603 | 16 | <$5M | AI Deep Dive |
| Lily Pad Pediatrics LLC | Health Care and Social Assistance | $204,577 | $207,083 | 18 | $5.6M | AI Deep Dive |
| Family Clinic INC | Health Care and Social Assistance | $200,035 | $200,796 | 22 | $6.9M | AI Deep Dive |
| Care for You Social Services LLC | Health Care and Social Assistance | $195,582 | $197,478 | 61 | $9.9M | AI Deep Dive |
| Care for You Social Services LLC | Health Care and Social Assistance | $195,582 | $197,315 | 61 | $10.4M | AI Deep Dive |
| Fried Chicken King INC | Accommodation and Food Services | $192,698 | $194,903 | 33 | $5.9M | AI Deep Dive |
| George Raymond Williams MD LLC | Health Care and Social Assistance | $189,607 | $191,824 | 18 | $5.6M | AI Deep Dive |