| The Hospital Service District of West Feliciana Parish Louis | Health Care and Social Assistance | $1,871,702 | $1,890,315 | 149 | N/A | Research |
| Red Stick Armature Works, Inc. | Other Services (except Public Administration) | $1,182,865 | $1,186,727 | 72 | $15.5M | Research |
| Red Stick Armature Works Inc. | Other Services (except Public Administration) | $1,177,112 | $1,189,962 | 70 | $15.0M | Research |
| St. Francisville Country Manor, LLC | Health Care and Social Assistance | $658,400 | $665,606 | 97 | $16.5M | Research |
| The Francis Southern Table and Bar LLC | Accommodation and Food Services | $573,720 | $577,848 | 125 | $22.2M | Research |
| The Francis Southern Table and Bar LLC | Accommodation and Food Services | $409,800 | $414,672 | 120 | $21.3M | Research |
| Clark Crain Autoplex of St. Francisville La LLC | Retail Trade | $373,422 | $376,835 | 41 | $10.3M | Research |
| Clark Crain Autoplex of St. Francisville | Retail Trade | $302,800 | $305,693 | 43 | $10.8M | Research |
| Daniel Services, LLC | Health Care and Social Assistance | $294,100 | $295,889 | 31 | $9.7M | Research |
| Ssc Dental Center, L.l.c. | Health Care and Social Assistance | $269,655 | $217,731 | 19 | <$5M | Research |
| Spinks Construction INC | Construction | $218,100 | $220,008 | 31 | $35.3M | Research |
| Spinks Construction, Inc. | Construction | $218,100 | $219,730 | 31 | $35.3M | Research |
| Sullivan Dental Center | Health Care and Social Assistance | $200,000 | $202,194 | 4 | <$5M | Research |
| Coastal Ecology Group, LLC | Professional, Scientific, and Technical Services | $179,360 | $180,237 | 9 | <$5M | Research |
| Coastal Ecology Group, LLC | Professional, Scientific, and Technical Services | $179,360 | $180,501 | 9 | <$5M | Research |
| Howell Foundry LLC | Manufacturing | $160,390 | $161,343 | 12 | <$5M | Research |
| Aucoin Timber Company LLC | Agriculture, Forestry, Fishing and Hunting | $159,603 | $161,580 | 13 | <$5M | Research |
| Magnolia Cafe INC | Accommodation and Food Services | $154,911 | $156,916 | 23 | <$5M | Research |
| Maginnis Construction Company, LLC | Construction | $151,832 | $153,304 | 9 | $10.3M | Research |
| Patricia M. Schneider MD Pediatric Clinic | Health Care and Social Assistance | $150,442 | $151,391 | 13 | <$5M | Research |
| Patricia M. Schneider MD Pediatric Clinic | Health Care and Social Assistance | $149,532 | $150,653 | 14 | <$5M | Research |
| General Pipe & Industrial Constructors - La, LLC | Other Services (except Public Administration) | $149,167 | $151,090 | 10 | <$5M | Research |
| Cecil Graves Chevrolet, INC | Retail Trade | $142,500 | $143,858 | 11 | <$5M | Research |
| Stamey Industrial Services | Construction | $136,800 | $138,407 | 29 | $33.0M | Research |
| Restaurant 1796 LLC | Accommodation and Food Services | $132,365 | $133,328 | 24 | <$5M | Research |