| Clhg-Ville Platte, LLC | Health Care and Social Assistance | $1,968,322 | $0 | 268 | $53.2M | Research |
| Ville Plattie Iron Works, Inc. | Manufacturing | $1,058,707 | $1,040,964 | 99 | $25.9M | Research |
| Ville Plattie Iron Works, Inc. | Manufacturing | $1,028,899 | $1,036,285 | 98 | $25.7M | Research |
| Evangeline Home Health LLC | Health Care and Social Assistance | $599,600 | $602,902 | 113 | $19.4M | Research |
| Sacred Heart School | Educational Services | $416,800 | $421,721 | 69 | N/A | Research |
| Medical Resources & Guidance Region 4 INC | Health Care and Social Assistance | $397,675 | $401,685 | 55 | $9.4M | Research |
| Ty Energy Services, LLC | Transportation and Warehousing | $389,753 | $392,443 | 54 | $14.4M | Research |
| First Choice Medical Staffing INC | Administrative and Support and Waste Management | $319,040 | $260,498 | 100 | $15.7M | Research |
| Truth Faith 2 LLC | Health Care and Social Assistance | $318,994 | $323,123 | 140 | $25.5M | Research |
| Soileau Industries INC | Manufacturing | $231,982 | $233,251 | 20 | $19.8M | Research |
| Cajun Central Incorporated | Unknown | $220,312 | $222,636 | 41 | N/A | Research |
| True Home Care LLC | Health Care and Social Assistance | $212,342 | $215,309 | 58 | $9.9M | Research |
| Teet's Food Store INC | Retail Trade | $207,087 | $208,335 | 46 | $11.5M | Research |
| Preferred Living, Inc. | Health Care and Social Assistance | $199,087 | $200,112 | 54 | $9.2M | Research |
| Doug Ashy Building Materials of Ville Platte, L.l.c. | Retail Trade | $196,300 | $198,399 | 24 | <$5M | Research |
| Unlimited Home Care of Louisiana INC | Health Care and Social Assistance | $183,789 | $186,607 | 64 | $11.0M | Research |
| Southern Comfort Community Homes, LLC | Health Care and Social Assistance | $172,943 | $174,075 | 88 | $14.3M | Research |
| Vidrine Community Clinic, L.l.c. | Health Care and Social Assistance | $154,665 | $156,379 | 18 | $5.6M | Research |
| Beyond the Curve Pediatrics LLC | Health Care and Social Assistance | $137,500 | $138,329 | 33 | $10.4M | Research |
| Charles J. Aswell Iii, M.d. Professional Medical Corporation | Health Care and Social Assistance | $137,385 | $138,405 | 11 | <$5M | Research |
| Charles J Aswell III M.d P.m.c. | Health Care and Social Assistance | $137,385 | $138,202 | 11 | <$5M | Research |
| J Ronald Landreneau & Associates Inc. | Professional, Scientific, and Technical Services | $135,375 | $136,439 | 12 | <$5M | Research |
| J. Ronald Landreneau & Assoc. Inc. | Professional, Scientific, and Technical Services | $135,375 | $136,759 | 9 | <$5M | Research |
| Champagnes Quality Foods, INC | Retail Trade | $135,317 | $136,764 | 30 | $7.5M | Research |
| Walker & Sons, Inc. | Manufacturing | $133,696 | $134,661 | 9 | <$5M | Research |