| City of Caribou | Health Care and Social Assistance | $4,787,700 | $4,855,925 | 250 | N/A | Research |
| Aroostook Mental Health Services, Inc. | Health Care and Social Assistance | $2,750,000 | $2,782,160 | 184 | N/A | Research |
| Caribou Nursing Home, Inc. | Health Care and Social Assistance | $1,656,400 | $1,674,144 | 265 | $45.1M | Research |
| Pines Health Services | Health Care and Social Assistance | $1,630,000 | $1,653,816 | 151 | N/A | Research |
| S.w. Collins Co. | Retail Trade | $1,024,400 | $0 | 109 | $22.5M | Research |
| Aroostook Home Health Services | Health Care and Social Assistance | $614,900 | $609,342 | 168 | N/A | Research |
| Soderberg Company INC | Construction | $587,039 | $590,626 | 54 | $61.5M | Research |
| Soderberg Company INC | Construction | $531,133 | $534,171 | 52 | $59.2M | Research |
| County Physical Therapy LLC | Health Care and Social Assistance | $479,290 | $485,334 | 56 | $15.1M | Research |
| County Physical Therapy, LLC | Health Care and Social Assistance | $462,400 | $465,084 | 44 | $11.9M | Research |
| Kbs Enterprises INC | Accommodation and Food Services | $389,159 | $391,462 | 60 | $18.8M | Research |
| Caribou F-M, Inc. | Retail Trade | $343,630 | $345,795 | 37 | $9.3M | Research |
| Kbs Enterprises, INC | Accommodation and Food Services | $276,835 | $278,427 | 60 | $18.8M | Research |
| Gf Marketing INC | Agriculture, Forestry, Fishing and Hunting | $231,460 | $216,551 | 40 | <$5M | Research |
| Gf Marketing INC | Agriculture, Forestry, Fishing and Hunting | $203,210 | $204,712 | 40 | <$5M | Research |
| Northern Maine Development Commission and Eastern Maine Deve | Public Administration | $192,900 | $193,934 | 13 | N/A | Research |
| Emerald Valley Ranches, LLC | Agriculture, Forestry, Fishing and Hunting | $183,700 | $185,270 | 18 | <$5M | Research |
| Family Eye Care | Health Care and Social Assistance | $171,927 | $173,880 | 11 | <$5M | Research |
| R.l.w. Management, Inc. | Real Estate and Rental and Leasing | $167,600 | $169,034 | 25 | <$5M | Research |
| Joseph Sleeper and Sons, INC | Retail Trade | $162,600 | $164,159 | 50 | $15.1M | Research |
| Beaulieu's Auto INC | Other Services (except Public Administration) | $153,300 | $154,164 | 16 | <$5M | Research |
| Staples Construction | Construction | $152,200 | $153,079 | 15 | $17.1M | Research |
| Professional Home Nursing, INC | Health Care and Social Assistance | $150,000 | $151,122 | 33 | $5.7M | Research |
| Craig Mavor-Small | Health Care and Social Assistance | $149,999 | $150,225 | 11 | <$5M | Research |
| Gurrette Farms Corp | Agriculture, Forestry, Fishing and Hunting | $149,773 | $140,064 | 20 | <$5M | Research |