| Lakeside Market, Inc. | Retail Trade | $164,100 | $165,595 | 39 | $13.1M |  Research |
| Brett Dinovi & Associates North, LLC | Health Care and Social Assistance | $148,744 | $150,146 | 21 | <$5M | Research |
| Waterboro Village Pediatrics, | Health Care and Social Assistance | $140,625 | $141,969 | 15 | <$5M | Research |
| J. D.'s Package Store, Inc. | Retail Trade | $114,800 | $115,492 | 18 | <$5M | Research |
| Oracle Management Ii, Inc. | Accommodation and Food Services | $98,500 | $99,241 | 16 | <$5M | Research |
| Town Line Deli INC | Retail Trade | $91,300 | $91,673 | 28 | $7.0M | Research |
| Camp Laughing Loon | Accommodation and Food Services | $90,400 | $90,842 | 14 | N/A | Research |
| F. M. Abbott Power Equipment, Inc. | Retail Trade | $86,700 | $87,382 | 10 | <$5M | Research |
| Educated Insurance & Retirement LLC | Finance and Insurance | $52,000 | $52,454 | 5 | <$5M | Research |
| Jophil & Associates LLC | Construction | $48,617 | $49,110 | 7 | $8.0M | Research |
| Big Guys Landscaping INC | Administrative and Support and Waste Management | $47,600 | $48,015 | 9 | <$5M | Research |
| Jophil & Associates, LLC | Construction | $46,500 | $46,908 | 5 | <$5M | Research |
| Lauzier Fine Home Builders LLC | Construction | $44,100 | $44,248 | 5 | <$5M | Research |
| Children's Challenge Child Care Center LLC | Health Care and Social Assistance | $42,500 | $42,859 | 9 | <$5M | Research |
| Rsd Management Corporation | Administrative and Support and Waste Management | $38,900 | $39,200 | 9 | <$5M | Research |
| William Earl | Accommodation and Food Services | $31,719 | $31,863 | 6 | <$5M | Research |
| Roof Pro LLC | Construction | $30,017 | $30,132 | 7 | <$5M | Research |
| Binette Insurance Agency, Inc. | Finance and Insurance | $27,000 | $27,224 | 5 | <$5M | Research |
| Woodsome's Feeds and Needs | Retail Trade | $21,045 | $21,150 | 4 | <$5M | Research |
| Margaret Brady | Administrative and Support and Waste Management | $20,930 | $21,049 | 7 | <$5M | Research |
| We the People Trucking LLC | Transportation and Warehousing | $20,800 | $20,859 | 1 | <$5M | Research |
| William D Earl DBA Vandy's | Accommodation and Food Services | $18,500 | $18,616 | 4 | <$5M | Research |
| Advantage Custom Homes INC | Construction | $18,200 | $18,306 | 3 | <$5M | Research |
| Rsd Graphics, Inc. | Manufacturing | $16,800 | $16,881 | 3 | <$5M | Research |
| Advantage Custom Homes, Inc. | Construction | $16,200 | $16,291 | 3 | <$5M | Research |