| Johnson & Jordan, Inc. | Construction | $3,552,200 | $3,597,589 | 292 | $92.4M | Research |
| Rc Moore, Inc. | Transportation and Warehousing | $3,433,200 | $3,474,116 | 261 | $52.6M | Research |
| Maine Center for Cancer Medicine and Blood Disorders PA | Health Care and Social Assistance | $3,313,100 | $3,352,676 | 199 | $62.5M | Research |
| N. E. Tech-Air, Inc. | Construction | $2,216,875 | $2,243,539 | 205 | $64.9M | Research |
| Morrison Center | Health Care and Social Assistance | $1,874,070 | $1,890,989 | 244 | N/A | Research |
| Hospice of Southern Maine | Health Care and Social Assistance | $1,856,540 | $1,867,527 | 123 | N/A | Research |
| Maine Life Care Retirement Community INC | Health Care and Social Assistance | $1,768,632 | $1,779,195 | 219 | N/A | Research |
| Direct Mail of Maine INC | Manufacturing | $1,645,567 | $1,667,691 | 133 | $131.9M | Research |
| Direct Mail of Maine INC | Manufacturing | $1,619,600 | $1,636,471 | 136 | $134.9M | Research |
| Aaa Energy Service Co | Construction | $1,304,500 | $1,311,648 | 74 | $23.4M | Research |
| North East Mobile Health Services | Health Care and Social Assistance | $1,251,600 | $1,260,035 | 150 | $34.8M | Research |
| Portland Air Freight, Inc. | Transportation and Warehousing | $1,179,100 | $1,186,928 | 89 | $17.9M | Research |
| Fielding's Oil Co. Inc. | Retail Trade | $1,061,700 | $1,068,631 | 95 | $22.7M | Research |
| Toddle Inn Day Care, Inc. | Health Care and Social Assistance | $919,845 | $927,076 | 136 | $22.0M | Research |
| Toddle Inn Day Care, Inc. | Health Care and Social Assistance | $919,700 | $927,620 | 147 | $23.8M | Research |
| Coastal Womens Healthcare | Health Care and Social Assistance | $867,500 | $872,634 | 68 | $21.3M | Research |
| Violette Home Care, LLC | Health Care and Social Assistance | $850,000 | $855,619 | 180 | $30.8M | Research |
| Violette Home Care INC | Health Care and Social Assistance | $838,735 | $842,090 | 133 | $22.8M | Research |
| Beauregard Equipment, Inc. | Wholesale Trade | $831,800 | $836,606 | 57 | $17.5M | Research |
| Landry/french Construction Company | Construction | $826,300 | $830,730 | 48 | $54.7M | Research |
| Sawdran, LLC | Retail Trade | $786,000 | $791,943 | 56 | $14.1M | Research |
| Risbara Bros. Construction Co., Inc. | Construction | $717,500 | $723,633 | 46 | $14.0M | Research |
| Bei Capelli INC | Other Services (except Public Administration) | $676,810 | $681,202 | 63 | $12.0M | Research |
| Maine Properties, LLC | Real Estate and Rental and Leasing | $670,100 | $675,956 | 74 | $11.1M | Research |
| It'llbe, LLC | Manufacturing | $639,324 | $643,231 | 61 | $21.5M | Research |