| Hadley Farms, Inc. | Manufacturing | $1,936,900 | $1,957,626 | 195 | $68.8M |  Research |
| Dpr Enterprises Incorporated | Accommodation and Food Services | $578,080 | $581,074 | 86 | $26.9M | Research |
| Huntzberry Brothers Inc. | Transportation and Warehousing | $457,139 | $461,583 | 45 | $6.8M | Research |
| Curtain Wall Specialists INC | Construction | $306,300 | $308,563 | 31 | $7.2M | Research |
| Pro-Fabricators INC | Manufacturing | $225,000 | $226,213 | 15 | <$5M | Research |
| Enterprise Security Solutions | Construction | $171,843 | $172,709 | 17 | $19.4M | Research |
| Cavetown Planing Mill Copmany and Subsidiaries | Manufacturing | $171,375 | $171,619 | 14 | $13.9M | Research |
| Jim Mace Ag & Auto Body Shop Inc. | Other Services (except Public Administration) | $152,303 | $153,860 | 10 | <$5M | Research |
| Jim Mace Ag & Auto Body Shop INC | Other Services (except Public Administration) | $152,300 | $154,051 | 10 | <$5M | Research |
| Smithsburg Cleaners Inc. | Other Services (except Public Administration) | $150,000 | $151,089 | 5 | <$5M | Research |
| Smithsburg Emergency Medical Services | Health Care and Social Assistance | $121,300 | $123,039 | 15 | N/A | Research |
| Jernigan's Environmental Services, Inc. | Construction | $118,200 | $119,068 | 9 | $10.3M | Research |
| Western Maryland Concrete Inc. | Construction | $117,216 | $117,692 | 15 | $5.1M | Research |
| Jernigans Environmental Services INC | Construction | $113,697 | $114,542 | 10 | <$5M | Research |
| Dr Painting LLC | Construction | $112,173 | $0 | 15 | <$5M | Research |
| Western Maryland Concrete, Inc. | Construction | $100,500 | $87,307 | 14 | <$5M | Research |
| Dr Painting LLC | Construction | $94,100 | $95,302 | 11 | <$5M | Research |
| My Favorite Place | Health Care and Social Assistance | $84,500 | $83,636 | 23 | <$5M | Research |
| Smithsburg Pharmacy LLC | Retail Trade | $76,232 | $77,101 | 6 | <$5M | Research |
| Compass Concrete, Inc. | Construction | $68,777 | $69,740 | 5 | <$5M | Research |
| 78 Acres, LLC | Agriculture, Forestry, Fishing and Hunting | $66,755 | $67,426 | 8 | <$5M | Research |
| Thomas M Nussear Dds, LLC | Health Care and Social Assistance | $63,167 | $63,743 | 5 | <$5M | Research |
| Thomas M Nussear DDS LLC | Health Care and Social Assistance | $63,167 | $63,476 | 5 | <$5M | Research |
| Corelinx Inc. | Information | $60,900 | $61,443 | 6 | <$5M | Research |
| Bme Business Systems LLC | Professional, Scientific, and Technical Services | $59,300 | $56,523 | 5 | <$5M | Research |