| Labornow, INC | Administrative and Support and Waste Management | $10,000,000 | $10,109,315 | 500 | $78.7M |  Research |
| Daniel J Quirk INC | Retail Trade | $5,789,485 | $5,870,379 | 115 | $29.0M | Research |
| Corcoran Management Company, INC | Real Estate and Rental and Leasing | $5,694,868 | $0 | 348 | $52.2M | Research |
| Dotcom.team Llc, the | Professional, Scientific, and Technical Services | $5,000,000 | $5,056,438 | 230 | $47.6M | Research |
| Braintree Laboratories Inc. | Manufacturing | $3,993,419 | $0 | 213 | $211.3M | Research |
| Sealcoating, INC | Construction | $3,597,170 | $3,639,437 | 150 | $46.5M | Research |
| Trustees of Thayer Academy | Educational Services | $3,410,350 | $3,449,569 | 240 | $28.8M | Research |
| Roman Catholic Archbishop of Boston | Other Services (except Public Administration) | $3,135,850 | $3,176,097 | 192 | N/A | Research |
| Symmons Industries, Inc. | Manufacturing | $2,572,200 | $2,601,711 | 147 | $35.9M | Research |
| O'connor & Drew PC | Professional, Scientific, and Technical Services | $2,386,745 | $2,372,743 | 120 | $38.2M | Research |
| Superior Bindery INC | Manufacturing | $2,003,794 | $2,026,028 | 158 | $156.7M | Research |
| Local Motion INC | Transportation and Warehousing | $1,894,047 | $1,906,034 | 205 | $78.8M | Research |
| Green Rabbit Holdings Inc. | Wholesale Trade | $1,875,067 | $1,885,521 | 160 | $41.2M | Research |
| Local Motion INC | Transportation and Warehousing | $1,798,642 | $1,812,243 | 196 | $75.4M | Research |
| Kevin P Martin & Associates, PC | Professional, Scientific, and Technical Services | $1,784,900 | $1,799,619 | 92 | $29.3M | Research |
| Weymouth Hingham Motor Sales INC | Other Services (except Public Administration) | $1,775,900 | $1,791,859 | 139 | $27.2M | Research |
| Fire King Baking Co., Inc. | Manufacturing | $1,745,862 | $1,761,599 | 219 | $77.3M | Research |
| Fire King Baking Co., Inc. | Manufacturing | $1,745,700 | $1,765,118 | 190 | $67.1M | Research |
| South Shore Elder Services | Health Care and Social Assistance | $1,685,000 | $1,711,406 | 145 | N/A | Research |
| Professional Auto Detailing Center Inc. | Other Services (except Public Administration) | $1,659,500 | $1,672,640 | 140 | $27.4M | Research |
| Professional Auto Detailing Center Inc. | Other Services (except Public Administration) | $1,659,500 | $1,670,594 | 130 | $25.5M | Research |
| 95 Commercial LLC | Health Care and Social Assistance | $1,653,887 | $1,678,879 | 297 | $50.5M | Research |
| 700 Elm LLC | Accommodation and Food Services | $1,650,460 | $1,665,563 | 175 | $54.7M | Research |
| S & P Consultants INC | Professional, Scientific, and Technical Services | $1,584,525 | $1,594,912 | 59 | $12.2M | Research |
| S & P Consultants, Inc. | Professional, Scientific, and Technical Services | $1,584,500 | $1,598,937 | 86 | $17.8M | Research |