| North Suffolk Mental Health Association Inc. | Health Care and Social Assistance | $7,738,325 | $7,783,695 | 500 | $89.0M |  Research |
| Kayem Foods INC | Manufacturing | $5,791,169 | $5,858,759 | 393 | $138.7M | Research |
| Chelsea Jewish Green House Inc. | Health Care and Social Assistance | $2,579,605 | $2,464,776 | 262 | $44.6M | Research |
| Muffin Town | Manufacturing | $2,542,522 | $2,572,114 | 319 | $112.6M | Research |
| Delta Management Associates INC | Administrative and Support and Waste Management | $2,451,475 | $1,504,394 | 1 | <$5M | Research |
| State Garden INC | Wholesale Trade | $2,426,961 | $2,454,622 | 170 | $43.8M | Research |
| Signature Breads, Inc. | Manufacturing | $2,181,700 | $2,207,093 | 211 | $74.5M | Research |
| Night Shift Brewing, INC | Wholesale Trade | $2,044,759 | $2,068,558 | 164 | $42.2M | Research |
| Eastpointe Rehab Center LLC | Health Care and Social Assistance | $1,977,742 | $1,996,970 | 224 | $38.1M | Research |
| Eastpointe Rehab Center LLC | Health Care and Social Assistance | $1,977,742 | $1,995,047 | 224 | $38.1M | Research |
| The Architectural Team, Inc. | Professional, Scientific, and Technical Services | $1,874,852 | $1,885,074 | 89 | $27.6M | Research |
| Delta Management Associates INC | Administrative and Support and Waste Management | $1,551,747 | $1,563,226 | 136 | $25.7M | Research |
| Chelsea Jewish Nursing Home Inc. | Health Care and Social Assistance | $1,489,375 | $1,510,389 | 138 | $23.5M | Research |
| Yell-O-Glow Corporation | Wholesale Trade | $1,350,900 | $1,362,420 | 110 | $28.3M | Research |
| Williamson Electrical Company | Construction | $1,272,200 | $1,288,774 | 71 | $23.4M | Research |
| Rapid Flow, Inc. | Administrative and Support and Waste Management | $1,092,107 | $1,097,523 | 40 | $7.6M | Research |
| Chelsea Jewish Lifecare INC | Health Care and Social Assistance | $971,312 | $984,139 | 46 | $7.8M | Research |
| Community Action Programs Inter-City, INC | Health Care and Social Assistance | $952,500 | $743,045 | 128 | N/A | Research |
| Rapid Flow, Inc. | Administrative and Support and Waste Management | $951,700 | $956,786 | 60 | $11.4M | Research |
| Eagle Air Freight INC | Transportation and Warehousing | $926,400 | $934,532 | 71 | $10.7M | Research |
| Interra Innovation, Inc. | Manufacturing | $914,765 | $922,261 | 55 | $54.6M | Research |
| Gem Auto Parts Co INC | Retail Trade | $854,355 | $861,681 | 90 | $18.6M | Research |
| Gem Auto Parts Co. INC | Retail Trade | $854,355 | $863,858 | 110 | $22.7M | Research |
| Carbone Sheet Metal Corporation | Manufacturing | $853,715 | $860,560 | 55 | $13.4M | Research |
| Lifestyle Transportation | Transportation and Warehousing | $836,755 | $844,146 | 58 | $17.8M | Research |