| New England Authentic Eats LLC | Accommodation and Food Services | $10,000,000 | $10,113,699 | 500 | $88.8M |  Research |
| Toward Independent Living and Learning Inc. | Health Care and Social Assistance | $6,950,287 | $7,008,746 | 500 | N/A | Research |
| Riverside Community Care INC | Health Care and Social Assistance | $3,500,000 | $3,511,181 | 500 | $85.1M | Research |
| Delta Projects, Inc. | Health Care and Social Assistance | $2,766,670 | $2,796,990 | 345 | N/A | Research |
| Alimed, Inc. | Wholesale Trade | $2,404,300 | $2,431,505 | 180 | $55.1M | Research |
| Macfarlane Energy, Inc. | Retail Trade | $1,645,943 | $1,574,965 | 100 | $23.9M | Research |
| Hopewell Inc. | Health Care and Social Assistance | $1,595,000 | $1,604,526 | 137 | N/A | Research |
| Dedham Country Day School | Educational Services | $1,427,965 | $1,441,729 | 85 | N/A | Research |
| Rashi School, Inc. | Educational Services | $1,384,700 | $1,414,160 | 20 | N/A | Research |
| Greater Boston Urology LLC | Health Care and Social Assistance | $1,137,800 | $1,145,874 | 99 | $31.1M | Research |
| Gallagher Concrete Construction Inc. | Construction | $1,129,495 | $1,139,181 | 35 | $8.1M | Research |
| Gallagher Concrete Construction, INC | Construction | $1,109,100 | $1,122,531 | 25 | $5.8M | Research |
| Arc Advisory Group Inc. | Professional, Scientific, and Technical Services | $1,011,787 | $1,005,350 | 42 | <$5M | Research |
| Ursuline Academy Dedham INC | Educational Services | $933,000 | $940,183 | 125 | N/A | Research |
| Waldron H Rand & Company PC | Professional, Scientific, and Technical Services | $906,130 | $912,684 | 50 | $15.9M | Research |
| American Green Building Services, INC | Administrative and Support and Waste Management | $779,913 | $789,316 | 229 | $49.6M | Research |
| Halfway Cafe Inc. | Accommodation and Food Services | $776,461 | $785,396 | 60 | $10.7M | Research |
| American Green Building Services INC | Administrative and Support and Waste Management | $753,765 | $761,345 | 229 | $49.6M | Research |
| Econo Tennis Management | Arts, Entertainment, and Recreation | $734,735 | $739,756 | 98 | $13.7M | Research |
| K C & Company INC | Other Services (except Public Administration) | $711,878 | $717,827 | 87 | $16.6M | Research |
| Acmeware, Inc. | Professional, Scientific, and Technical Services | $654,700 | $661,893 | 26 | $5.4M | Research |
| Econo Tennis Management Corp | Arts, Entertainment, and Recreation | $647,219 | $592,686 | 59 | $8.3M | Research |
| Greater Boston Home Health Care Services, Inc. | Health Care and Social Assistance | $597,700 | $580,281 | 153 | $24.8M | Research |
| Awh Dedham Hotel LLC | Accommodation and Food Services | $569,958 | $573,768 | 21 | $6.6M | Research |
| Fed Corp | Construction | $562,500 | $566,122 | 25 | $7.7M | Research |