| Helfrich Brothers Boiler Works, Inc. | Manufacturing | $5,003,790 | $5,060,545 | 297 | $72.6M | Research |
| Little Sprouts, LLC | Health Care and Social Assistance | $4,740,032 | $4,792,627 | 20 | <$5M | Research |
| Elder Services of the Merrimack Valley, Inc. | Health Care and Social Assistance | $4,178,800 | $4,234,749 | 495 | N/A | Research |
| The Gem Group, Inc. | Manufacturing | $4,162,600 | $4,207,647 | 316 | $111.5M | Research |
| Energy North Incorporated | Retail Trade | $3,980,940 | $4,026,094 | 475 | $113.5M | Research |
| Fidelity House, INC | Health Care and Social Assistance | $3,311,600 | $3,350,787 | 423 | N/A | Research |
| Maestro-Connections Health Systems LLC | Health Care and Social Assistance | $2,975,600 | $0 | 95 | $16.3M | Research |
| Middle East Bakery, Inc. | Wholesale Trade | $2,859,500 | $2,672,660 | 275 | $70.8M | Research |
| Jackson Lumber and Millwork Co. Inc. | Retail Trade | $2,701,500 | $2,732,492 | 192 | $39.6M | Research |
| Helfrich Bros Boiler Works INC | Manufacturing | $2,000,000 | $2,016,712 | 282 | $68.9M | Research |
| Soep Painting Corporatio | Construction | $2,000,000 | $2,014,389 | 106 | $26.8M | Research |
| Charles Daher's Commonwealth Motors Inc. | Retail Trade | $1,938,815 | $1,954,379 | 155 | $39.1M | Research |
| Charles Daher's Commonwealth Motors INC | Retail Trade | $1,938,814 | $1,974,350 | 155 | $39.1M | Research |
| Brodie, Inc. | Other Services (except Public Administration) | $1,915,608 | $1,934,551 | 103 | $22.1M | Research |
| Merrimack Valley Ymca Inc. | Other Services (except Public Administration) | $1,862,690 | $1,877,592 | 212 | N/A | Research |
| Central Catholic High School of Law, Inc. | Educational Services | $1,860,517 | $1,882,688 | 137 | N/A | Research |
| Maestro-Connections Health Systems LLC | Health Care and Social Assistance | $1,853,200 | $1,616,630 | 95 | $16.3M | Research |
| Bagel Boy, Inc. | Manufacturing | $1,795,200 | $1,807,348 | 181 | $47.4M | Research |
| Fcp, INC | Health Care and Social Assistance | $1,759,810 | $1,584,096 | 205 | N/A | Research |
| New England Neurological Associates, PC | Health Care and Social Assistance | $1,746,900 | $1,766,941 | 105 | $33.0M | Research |
| The Merrimack Valley Young Men's Christian Association, Inc. | Other Services (except Public Administration) | $1,642,050 | $1,661,207 | 430 | N/A | Research |
| Cube 3 Studio LLC | Professional, Scientific, and Technical Services | $1,637,222 | $1,645,545 | 107 | $33.2M | Research |
| Cube 3 Studio LLC | Professional, Scientific, and Technical Services | $1,637,222 | $1,655,459 | 101 | $31.3M | Research |
| Lawrence Staffing Services | Administrative and Support and Waste Management | $1,239,415 | $1,249,089 | 150 | $23.6M | Research |
| Tallman Eye Associates, PC | Health Care and Social Assistance | $1,223,200 | $1,238,218 | 90 | $16.0M | Research |